Figures & data
Figure 1 Epigenetic factors are mediators of inflammation and chronic inflammatory disease.
Notes: environmental triggers of inflammation initiate a series of regulated molecular events that are mediated by epigenetic, genetic, as well as other factors (such as the microbiome which is not discussed here). This leads to the initiation and resolution of physiological inflammation and the restoration of homeostasis. Epigenetic modifications also contribute to failure of the inflammatory response to resolve, leading to tissue damage and chronic inflammatory disease.
