https://orcid.org/0000-0003-3563-8998
Figures & data
Figure 1 Flow chart of patient enrollment and follow-up.
Abbreviations: AP, acute pancreatitis; NP, necrotizing pancreatitis; CT, computed tomography; MRI, magnetic resonance image.
Table 1 Definitions of the Observation Indicators
Figure 2 Surgical intervention for colonic complications.
Notes: (A) Surgical treatment of colonic fistula) Male, 51 years old, gallstone AP, onset 32 days due to infection CT examination revealed IPN-transverse colonic endovascular fistula, median approach pancreatic necrosectomy with terminal ileostomy was performed, patient’s infection was controlled; (B) Surgical treatment of colonic obstruction) Female, 47 years old, gallstone AP, 56 days after onset, left retroperitoneal approach for debridement, 2 months after surgery, colonic splenic area obstruction admitted, terminal ileostomy performed, obstruction relieved, 3 months after fistula, transverse colon-sigmoid lateral anastomosis performed, simultaneous ileostomy closed fistula; (C) Surgical treatment of colonic bleeding) Male, 35 years old, hyperlipidemic AP, 55d after onset, 10d after left retroperitoneal access debridement, drainage bleeding, Hb: 49g/L, spring coil embolization under DSA. (D) Surgical treatment of colonic bleeding) Female, 56 years old, hyperlipidemic AP, 42 days after onset, 7d after epigastric median approach debridement, bleeding from drainage tube, Hb: 61g/L, medical glue embolization under DSA.
Abbreviations: AP, acute pancreatitis; CT, computed tomography; IPN, infected pancreatic necrosis; Hb, hemoglobin; DSA, digital subtraction angiography.
Figure 3 Distribution, diagnosis and treatment of colonic complications.
Notes: (A) describes the sites of colonic fistula and colonic obstruction; (B) describes the arteries of origin of colonic hemorrhage; (C) describes the time of diagnosis of colonic complications in NP patients; (D) describes the intervention type in NP patients with colonic complications; (E) describes the time of intervention for colonic complications in NP patients.
Abbreviation: NP, necrotizing pancreatitis.
Table 2 Characteristics of the Necrotizing Pancreatitis Patients
Table 3 Comparison of Clinical Outcomes Between Two Groups Before PSM
Table 4 Baseline Data of the Two Groups After PSM
Table 5 Comparison of Clinical Outcomes Between Two Groups After PSM
Figure 4 The comparison of overall survival rate between two groups.
Notes: (A) The overall survival rate of NP patients during follow-up period before PSM. A total of 9 patients died, 42 patients were lost follow-up, and 205 patients survived. The average follow-up time was 39.78 ± 29.07 months; (B) The overall survival rate of NP patients during follow-up period after PSM. A total of 3 patients died, 6 patients were lost follow-up, and 43 patients survived. The average follow-up time was 40.17 ± 23.21 months; (C) The comparison of the overall survival rate between the two groups. In the colonic group, 15 patients died; 13 patients died during hospitalization, and 2 patients died during follow-up. In the no-colonic group, 12 patients died; 11 patients died during hospitalization and 1 patient died during follow-up. The overall survival rates of colonic group and no-colonic group were 88.0% and 77.8%, respectively (P =0.537).
Abbreviations: NP, necrotizing pancreatitis; PSM, propensity score-matched.
Table 6 The Long-Term Complication Between the Two Groups During the Follow-Up Period
Table 7 Quality of Life Rating Scale During the Follow-Up Period of Surviving Patients