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Journal of Inflammation Research Volume 16, 2023 - Issue
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REVIEW

Sparcl1 and Atherosclerosis

Xu Cheng1 Department of Cardiovascular Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China;2 Laboratory of Molecular Biology and Department of Biochemistry, Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-6629-5724View further author information
ORCID Icon,
Xinyan Chen2 Laboratory of Molecular Biology and Department of Biochemistry, Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China;3 Department of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of ChinaView further author information
,
Min Zhang3 Department of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of ChinaView further author information
,
Yufeng Wan4 Department of Otolaryngology-Head Neck Surgery, the Affiliated Chaohu Hospital of Anhui Medical University, Hefei, Anhui, 238001, People’s Republic of ChinaView further author information
,
Shenglin Ge1 Department of Cardiovascular Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0691-5936View further author information
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Xiaowen Cheng2 Laboratory of Molecular Biology and Department of Biochemistry, Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China;3 Department of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China;5 Anhui Province Key Laboratory of Translational Cancer Research, Bengbu Medical College, Bengbu, Anhui, 233030, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-9213-1312View further author information
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Pages 2121-2127 | Received 03 Feb 2023, Accepted 03 May 2023, Published online: 17 May 2023

Figures & data

Figure 1 The homology of SPARC with Sparc-1 is clearly seen by the overlap of the relevant colors in the figure. The gene schematic of SPARC is shown at the top of the figure, and the gene schematic of Sparcl1 is shown at the bottom. The number of corresponding amino acids is shown below the structural domain.

Figure 1 The homology of SPARC with Sparc-1 is clearly seen by the overlap of the relevant colors in the figure. The gene schematic of SPARC is shown at the top of the figure, and the gene schematic of Sparcl1 is shown at the bottom. The number of corresponding amino acids is shown below the structural domain.

Figure 2 Sparcl1 can affect cell differentiation through the BMP/TGF-β pathway.

Notes: Reproduced from Wang Y, Liu S, Yan Y, Li S, Tong H. SPARCL1 promotes C2C12 cell differentiation via BMP7-mediated BMP/TGF-β cell signaling pathway. Cell Death Dis. 2019;10:852. Creative Commons.Citation37
Figure 2 Sparcl1 can affect cell differentiation through the BMP/TGF-β pathway.

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