Figures & data
Abbreviations: AMPK, adenosine monophosphate-activated protein kinase; mTOR, mammalian target of rapamycin; PRAS40, proline-rich Akt substrate 40; TSC, tuberous sclerosis complex; RICTOR, rapamycin-insensitive companion of mTOR; Rheb, ras homolog enriched in the brain; mLST8, mammalian lethal with sec-13 protein 8; Raptor, regulatory associated protein of mTOR; Deptor, DEP domain-containing mTOR-interacting protein; mSIN1, mammalian stress-activated protein kinase (SAPK)-interacting protein 1.