https://orcid.org/0000-0002-0041-1614
Figures & data
Figure 1 Vascular response upon topical cinnamaldehyde 10% (A and B) and capsaicin 1000µg/20µL (C and D) application on the forearm in 12 healthy male subjects. The vascular response is expressed over time (mean ± SEM) as dermal blood flow within the area of application (DBFring, perfusion units[PUs]) ((A and C) black) or Flarearea (mm²) ((A and C) grey) before, ie at pre-drug baseline, (blank) and 18 ± 1 hours after oral intake of dexamethasone 10mg (full). Statistical analysis using Linear mixed models (fixed effect: dexamethasone treatment; random effect: subject; repeated statement: time point), significance level set at 0.05. Representative images of the vascular response at pre-challenge baseline and respectively 20 or 40 minutes after cinnamaldehyde 10% (B) and capsaicin 1000µg/20µL (D) application.
![Figure 1 Vascular response upon topical cinnamaldehyde 10% (A and B) and capsaicin 1000µg/20µL (C and D) application on the forearm in 12 healthy male subjects. The vascular response is expressed over time (mean ± SEM) as dermal blood flow within the area of application (DBFring, perfusion units[PUs]) ((A and C) black) or Flarearea (mm²) ((A and C) grey) before, ie at pre-drug baseline, (blank) and 18 ± 1 hours after oral intake of dexamethasone 10mg (full). Statistical analysis using Linear mixed models (fixed effect: dexamethasone treatment; random effect: subject; repeated statement: time point), significance level set at 0.05. Representative images of the vascular response at pre-challenge baseline and respectively 20 or 40 minutes after cinnamaldehyde 10% (B) and capsaicin 1000µg/20µL (D) application.](/cms/asset/9ab42daa-8d76-4cb9-aa1f-c41f2f5163bc/djir_a_12302582_f0001_c.jpg)