Figures & data
Figure 1 Study timeline with hypothetical patient journeys. Index date represents the date of the first pain drug prescription; Follow-up period represents from index date to the date of OA surgery or the end date of prescriptions, whichever occurred later.
Abbreviation: OA, osteoarthritis.
Figure 2 Flow of patient extraction.
Abbreviations: CLBP, chronic low back pain; MDV, Medical Data Vision Co., Ltd.; OA, osteoarthritis.
Table 1 Patient demographics and clinical characteristics at baseline
Table 2 Pain drug classes prescribed since the day of the first pain drug prescription (index date) for all patients combined (total) and patients from 2013 to 2017
Table 3 Treatment sequence of pain drug classes prescribed first to fifth line among patients with a follow-up period of ≥1 year
Table 4 Time to the first weak opioid prescription, treatment duration and dose, and number of drug classes prescribed before weak opioids
Table S1 Pain drug classes examined in this study
Table S2 Patients excluded from the CLBP cohort
Table S3 Surgery for OA patients
Table S4 Pain drug classes prescribed to patients with and without weak opioid prescription
Table S5 Baseline clinical characteristics of overall patients with and without weak opioid prescription