Knowledge Mapping of Acupuncture for Cancer Pain: A Scientometric Analysis (2000–2019)

Figures & data

Figure 1 Line chart of yearly output on acupuncture for cancer pain. The abscissa in the figure represents the year and the ordinate represents the total number of publications.

Table 1 Countries/Territories Contributed to Publications on Acupuncture for Cancer Pain from 2000 to 2019

No.	Country/ TerritoriesFrequency	Frequency	Centrality	Country/ TerritoriesCentrality
1	USA	196	0.90	Australia
2	Peoples R China	102	0.82	Peoples R China
3	England	54	0.63	Germany
4	South Korea	49	0.58	USA
5	Germany	28	0.33	South Korea
6	Taiwan (China)	22	0.27	England
7	Australia	19	0.22	Italy
8	Canada	17	0.22	Malaysia
9	Brazil	14	0.07	Canada
10	Sweden	10	0.00	Taiwan (China)
11	Italy	10	0.00	Brazil
12	France	6	0.00	Sweden
13	Israel	5	0.00	France
14	Malaysia	3	0.00	Israel
15	Japan	3	0.00	Japan

Notes: In this table, the other two identical columns represent different rankings. The left column of the table represents the Countries/ Territories that have published acupuncture treatment for cancer pain. The frequency of contribution is sorted from high to low. The column on the right represents the sorting from high to low according to centrality.

Table 2 Institutions Contributed to Publications on Acupuncture for Cancer Pain from 2000 to 2019

No.	InstitutionFrequency	Frequency	Centrality	InstitutionCentrality
1	Mem Sloan Kettering Canc Ctr	24	0.21	Univ Maryland
2	Kyung Hee Univ	22	0.20	Columbia Univ
3	Univ Penn	14	0.19	Kyung Hee Univ
4	Columbia Univ	11	0.18	Univ Texas MD Anderson Canc Ctr
5	Univ Exeter	10	0.18	Pusan Natl Univ
6	Univ Maryland	10	0.16	Univ Washington
7	Univ Texas MD Anderson Canc Ctr	9	0.10	Univ Michigan
8	Beijing Univ Chinese Med	8	0.09	Mem Sloan Kettering Canc Ctr
9	Guangzhou Univ Chinese Med	8	0.09	Harvard Med Sch
10	China Med Univ	7	0.08	Korea Inst Oriental Med
11	Univ Washington	6	0.06	Natl Cheng Kung Univ
12	Harvard Univ	6	0.05	Univ Pittsburgh
13	Leeds Metropolitan Univ	6	0.04	Univ Penn
14	Univ Pittsburgh	6	0.04	Beijing Univ Chinese Med
15	Korea Inst Oriental Med	6	0.04	China Med Univ

Notes: In this table, the two identical columns represent different rankings. The left column of the table represents the country/region that has published acupuncture treatment for cancer pain. The frequency of contribution is sorted from high to low. The column on the right represents the sorting from high to low according to centrality.

Abbreviations: Mem Sloan Kettering Canc Ct, Memorial Sloan Kettering Cancer Center; Kyung Hee Uni, Kyung Hee University; Univ Penn, University of Pennsylvania; Columbia Univ, Columbia University; Univ Exeter, University of Exeter; Univ Maryland, University of Maryland; Univ Texas MD Anderson Canc Ctr, University of Texas Anderson Cancer Center; Beijing Univ Chinese Med, Beijing University of Chinese Medicine; Guangzhou Univ Chinese Med, Guangzhou University of Chinese Medicine; China Med Univ, China Medical University; Univ Washington, University of Washington; Harvard Univ, Harvard University; Leeds Metropolitan Univ, Leeds Metropolitan University; Univ Pittsburgh, University of Pittsburgh; Korea Inst Oriental Med, Korea Institute of Oriental Medicine; Pusan Natl Univ, Pusan National University; Univ Michigan, University of Michigan; Harvard Med Sch, Harvard Medical School; Natl Cheng Kung Univ, National Cheng Kung University.

Figure 2 Network of countries/territories on acupuncture for cancer pain. The purple node in the middle of the annual ring means the influence and the significance of a country/territory. The larger the node and the more purple it exhibits, the greater is the importance of the country/territory.

Table 3 Institutions Engaged in Acupuncture for Cancer Pain That Details of Knowledge Clusters

Cluster-ID	Size	Silhouette	Mean (Year)	Label (LLR)	Label (MI)
0	13	0.975	2012	nationwide population-based study	chronic pain
1	12	0.972	2014	publication trend	chronic pain
2	9	0.796	2011	physical symptom	international conference
4	6	0.956	2011	breast cancer patient	inhibitor use

Figure 3 (A) Cluster map of institutions based on label clusters with title terms. The combination of symbols and numbers delegates the institutions’ study of similar categories. (B) Timeline zone of institutions on acupuncture for cancer pain. The purple node in the middle of the annual ring means the influence and the significance of the institution. Institutions with the homologous research category are on the same time horizon.

Table 4 Authors Contributed to Publications on Acupuncture for Cancer Pain from 2000 to 2019

No.	AuthorFrequency	Frequency	Centrality	AuthorCentrality
1	Mao JJ	17	0.09	Bao T
2	Ernst E	9	0.08	Mao JJ
3	Johnson MI	6	0.07	Greenlee H
4	Cassileth BR	6	0.05	Cohen L
5	Cohen L	6	0.04	Piulson L
6	Bao T	6	0.04	Vertosick E
7	Deng G	5	0.03	Deng G
8	Enblom A	5	0.03	Meghani SH
9	Garcia MK	5	0.02	Garcia MK
10	Lee JH	5	0.02	Lee JH
11	Paley CA	4	0.02	Bruner D
12	Greenlee H	4	0.02	Wei Q
13	Kim W	4	0.02	Li SQ
14	Bennett MI	4	0.01	Ernst E
15	Kim KH	4	0.01	Cassileth BR

Notes: In this table, the other two identical columns represent different rankings. The left column of the table represents the author that has published acupuncture treatment for cancer pain. The frequency of contribution is sorted from high to low. The column on the right represents the sorting from high to low according to centrality.

Table 5 Authors Engaged in Acupuncture for Cancer Pain That Details of Knowledge Clusters

Cluster-ID	Size	Silhouette	Mean (Year)	Label (LLR)	Label (MI)
0	11	0.884	2013	phase iia trial	supratentorial craniotomy
3	9	0.990	2014	multiple myeloma	supratentorial craniotomy
4	8	0.943	2015	randomized trial	supratentorial craniotomy
6	5	0.842	2014	supratentorial craniotomy	breast cancer patient

Figure 4 (A) Cluster map of authors based on label clusters with title terms. The combination of symbols and numbers delegates the authors’ study of similar categories. (B) Timeline zone of authors on acupuncture for cancer pain.

Table 6 Cited Reference Contributed to Co-Citations on Acupuncture for Cancer Pain from 2000 to 2019

No.	Cited ReferenceFrequency	Frequency	Centrality	Cited ReferenceCentrality
1	Crew KD (2010)^Citation32	35	0.56	Roscoe JA (2003)^Citation63
2	Alimi D (2003)^Citation33	35	0.54	Ho CM (1996)^Citation64
3	Garcia MK (2013)^Citation65	32	0.53	Dibble SL (2000)^Citation66
4	Choi TY (2012)^Citation55	31	0.53	Vickers AJ (1996)^Citation67
5	Schroeder S (2012)^Citation68	25	0.52	Crew KD (2007)^Citation69
6	Lee H (2005)^Citation70	24	0.39	Crew KD (2007)^Citation71
7	Donald GK (2011)^Citation72	22	0.39	Lu W (2005)^Citation73
8	Mao JJ (2014)^Citation74	22	0.34	Alimi D (2003)^Citation33
9	Bao T (2013)^Citation75	22	0.29	Oh B (2013)^Citation24
10	Vickers AJ (2012)^Citation76	21	0.27	Bao T (2013)^Citation75
11	Hershman DL (2014)^Citation77	19	0.27	Mehling WE (2007)^Citation78
12	Paley CA (2015)^Citation57	18	0.21	Gorin SS (2012)^Citation37
13	Shen JN (2000)^Citation79	17	0.21	Ezzo JM (2006)^Citation80
14	Molassiotis A (2012)^Citation39	15	0.20	Molassiotis A (2005)^Citation81
15	Vickers AJ (2004)^Citation45	15	0.18	Streitberger K (2003)^82

Notes: In this table, the other two identical columns represent different rankings. The left column of the table represents the cited references that have published acupuncture treatment for cancer pain. The frequency of contribution is sorted from high to low. The column on the right represents the sorting from high to low according to centrality.

Table 7 Cited Reference Engaged in Acupuncture for Cancer Pain That Details of Knowledge Clusters

Cluster-ID	Size	Silhouette	Mean (Year)	Label (LLR)	Label (MI)
0	32	0.815	1999	palliative cancer care	neck malignancies
1	29	0.893	2006	acupuncture	neck malignancies
2	27	0.950	2009	early-stage breast cancer	neck malignancies
3	26	0.904	2009	randomised clinical trial	neck malignancies
4	24	0.935	2011	cancer care	neck malignancies
5	22	0.977	1999	clinical oncology program multicenter study	neck malignancies
6	21	0.979	2015	comprehensive pain care	neck malignancies
7	19	0.980	2007	cancer-induced bone pain	neck malignancies
8	18	0.958	2002	cancer symptom management	neck malignancies
9	18	0.795	2003	acupuncture use	neck malignancies
10	18	0.960	2012	chemotherapy-induced peripheral neuropathy	bortezomib-induced peripheral neuropathy
11	17	0.949	2002	symptom management	symptom management
12	12	0.953	1999	psychosocial aspect	psychosocial aspect
13	8	0.991	2006	placebo effect	acupuncture
14	4	0.990	1998	neck malignancies	acupuncture

Figure 5 (A) Cluster map of cited reference based on label clusters with title terms. The combination of symbols and numbers delegates the cited references’ study of similar categories. (B) Timeline zone of cited reference on acupuncture for cancer pain.

Table 8 Keyword Contributed to Publications on Acupuncture for Cancer Pain from 2000 to 2019

No.	KeywordFrequency	Frequency	Centrality	KeywordCentrality
1	acupuncture	290	0.35	auricular acupuncture
2	pain	161	0.30	alternative medicine
3	cancer	97	0.24	complementary
4	quality of life	92	0.21	palliative care
5	management	91	0.21	chemotherapy induced nausea
6	breast cancer	82	0.21	acupuncture treatment
7	electroacupuncture	75	0.16	quality
8	randomized controlled trial	53	0.15	pain
9	therapy	52	0.15	neuropathic pain
10	alternative medicine	46	0.14	complementary therapy
11	complementary	43	0.13	quality of life
12	chemotherapy	43	0.12	cancer pain
13	women	37	0.12	expression
14	low back pain	32	0.12	adult
15	controlled trial	32	0.12	hypnosis
16	acupressure	32	0.11	prevalence
17	nausea	31	0.11	integrative medicine
18	prevalence	30	0.11	complementary medicine
19	neuropathic pain	30	0.11	oncology
20	cancer pain	29	0.11	xerostomia

Notes: In this table, the other two identical columns represent different rankings. The left column of the table represents keywords that have published acupuncture treatment for cancer pain. The frequency of contribution is sorted from high to low. The column on the right represents the sorting from high to low according to centrality.

Table 9 Keywords Engaged in Acupuncture for Cancer Pain That Details of Knowledge Clusters

Cluster-ID	Size	Silhouette	Mean (Year)	Label (LLR)	Label (MI)
0	22	0.765	2008	early-stage breast cancer	oral cancer pain
1	19	0.807	2006	clinical oncology program multicenter study	oral cancer pain
2	18	0.682	2005	molecular mechanism	oral cancer pain
3	18	0.797	2009	evidence-based integrative pain medicine	oral cancer pain
4	17	0.762	2007	western integrative medicine	oral cancer pain
5	13	0.802	2007	lung cancer	oral cancer pain
6	13	0.808	2007	normal cell telomere	oral cancer pain
7	13	0.840	2006	case series	integrative treatment
8	11	0.795	2011	potential vanilloid	oral cancer pain
9	11	0.856	2007	placebo effect	lung cancer
10	9	0.949	2005	pediatric oncology	lung cancer
11	9	0.923	2008	early breast cancer	oral cancer pain
12	9	0.937	2010	adult cancer patient	oral cancer pain
13	7	0.944	2011	PMA-mediated MMP-9 gene activation	lung cancer

Figure 6 (A) Cluster map of keyword based on label clusters with title terms. The combination of symbols and numbers delegates the keywords’ study of similar categories. (B) Timeline zone of keyword on acupuncture for cancer pain.

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