Prevalence of depression and receipt of antidepressant pharmacotherapy among patients with Parkinson’s disease: a national assessment of US office-based physician visits

Figures & data

Table 1 Characteristics of patients aged ≥20 years with a diagnosis of Parkinson’s disease: US office-based physician visits in 2013–2014

Characteristics	N	%
Total unweighted, n	174	−
Total weighted, n	3,180,324	100.0
Patient characteristics
Age group (years)
≤50	26,396	0.8
50–59	272,873	8.6
60–69	1,106,290	34.8
70–79	969,743	30.5
≥80	805,023	25.3
Sex
Female	1,509,593	47.5
Male	1,670,732	52.5
Race/ethnicity
White non-Hispanic	2,000,883	62.9
Black non-Hispanic	360,880	11.3
Hispanic	774,923	24.4
Other	43,639	1.4
Payment source
Private insurance	791,308	28.7
Medicare	1,804,954	65.4
Medicaid	5,829	0.2
Other	157,719	5.0
Comorbidities
Cerebrovascular disease	122,263	3.8
Chronic kidney disease or ESRD	26,887	0.8
Congestive heart failure	54,522	1.7
Hyperlipidemia	458,118	14.4
Hypertension	992,332	31.2
Heart disease: CAD, IHD, or previous MI	121,553	3.8
Physician specialty
General or family practice	385,925	12.1
Internal medicine	403,363	12.7
Psychiatry	73,683	2.3
Neurology	1,847,256	58.1
Other	470,097	14.8
Seen by primary care physician	760,194	24.3

Note: Parkinson’s disease is defined as ICD-9-CM code 332.0× in the primary, secondary, or tertiary diagnosis fields.

Abbreviations: CAD, coronary artery disease; ESRD, end-stage renal disease; ICD-9, International Classification of Diseases, 9th Revision; IHD, ischemic heart disease; MI, myocardial infarction.

Table 2 Depression screening and treatment provided to patients aged ≥20 years with a diagnosis of Parkinson’s disease: US office-based physician visits in 1990–1995 versus 2013–2014

Characteristic	1990–1995^Table Footnotea %	2013–2014 %
Prescribed an antidepressant^Table Footnoteb	8.6	29.8
Screened for depression^Table Footnotec	NA	5.6
Depression diagnosed^Table Footnoted	4.1	8.3
And prescribed an antidepressant^Table Footnoteb	3.2	7.2
Prescribed an antidepressant, as a proportion of those diagnosed	78.2	87.1
Depression diagnosed^Table Footnoted and/or indicated in record^Table Footnotee	NA	14.8
And prescribed an antidepressant^Table Footnoteb	NA	12.2
Prescribed an antidepressant, as a proportion of those with depression diagnosed or indicated in record	NA	82.3

Notes:

a Data from Sclar et al, 1998.²¹

b SSRIs, SNRIs, tricyclic antidepressants, tetracyclic antidepressants, MAOIs, and any other antidepressant medication recorded as Multum category 249.

c Reflects whether patient was screened for depressive disorder.

d Defined as ICD-9 codes of 296.2× (major depressive disorder, single episode), 296.3× (major depressive disorder, recurrent episode), 300.4 (dysthymic disorder), or 311 (depressive disorder, not elsewhere classified).

e Refers to a section of the questionnaire that asked: “Regardless of the diagnoses previously entered, does the patient now have…”. NA, not available because the item was not available in 1990–1995 or was not reported in the article by Sclar et al.²¹

Abbreviations: ICD-9, International Classification of Diseases, 9th Revision; MAOI, monoamine oxidase inhibitor; SNRI, selective norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor.

Sclar DA, Robison LM, Skaer TL, Galin RS. Depression in Parkinson’s disease: a national survey of office-based visits 1990-1995. Int J Geriatr Psychopharmacol. 1998;1:216–219.

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