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ORIGINAL RESEARCH

Safety and Performance of Hemostatic Powders

, , , , , & show all
Pages 133-144 | Received 09 Feb 2023, Accepted 16 May 2023, Published online: 08 Jun 2023

Figures & data

Figure 1 Test system to water absorption rate testing consisted of the burette, filter funnel, stand, clamps, and hose.

Figure 1 Test system to water absorption rate testing consisted of the burette, filter funnel, stand, clamps, and hose.

Figure 2 Test system to adhesion/cohesion capacity testing consisted of testing machine clamps, metal probe (150 mm length, 22 mm mount diameter), well (35.5 mm diameter and 17.2 mm height) filled with gelled sample.

Figure 2 Test system to adhesion/cohesion capacity testing consisted of testing machine clamps, metal probe (150 mm length, 22 mm mount diameter), well (35.5 mm diameter and 17.2 mm height) filled with gelled sample.

Figure 3 Endotoxin standard curve (R2=0.9811).

Figure 3 Endotoxin standard curve (R2=0.9811).

Figure 4 Cytotoxicity results.

Figure 4 Cytotoxicity results.

Table 1 Results of Cytotoxic Potential Assessment

Figure 5 Cell culture images of cytotoxic potential assessment.

Figure 5 Cell culture images of cytotoxic potential assessment.

Figure 6 Water absorption capacity (WAC) results per 0.5 g of product. p=0.1234; **p=0.0021; ****p<0.0001.

Abbreviation: ns, non-significant.
Figure 6 Water absorption capacity (WAC) results per 0.5 g of product. p=0.1234; **p=0.0021; ****p<0.0001.

Figure 7 Results of water absorption rate (WAR) for 0.1 g of hemostatic powders. *p=0.0332; ***p=0.00002; ****p<0.0001.

Figure 7 Results of water absorption rate (WAR) for 0.1 g of hemostatic powders. *p=0.0332; ***p=0.00002; ****p<0.0001.

Figure 8 Results of adhesion assay of hemostatic powders.**p=0.0021; ****p<0.0001.

Figure 8 Results of adhesion assay of hemostatic powders.**p=0.0021; ****p<0.0001.

Table 2 Endotoxins Concentration Results