Expression of MMP-15 and MMP-24 in atherosclerotic and nonatherosclerotic coronary arteries

Figures & data

Table 1 MMP-24, MMP-15, and GAPDH primers for RT-PCR (real-time polymerase chain reaction)

	Size (bp)	Tm (°C)	% GC	Sequencing
GAPDH
Forward primer	17	63	54.55	5′-TCACCATCTTCCAGGAG-3′
Reverse primer	20	62	52.38	5′-TCGAGGAGGCATTGCTGATGA-3′
MMP-15
Forward primer	24	59.01	54.17	5′-ACAACCGCGTCCTGGACAACTATC-3′
Reverse primer	24	58.94	54.17	5′-AAGAGCCAGTAGCGGTCACCTTTG-3′
MMP-24
Forward primer	23	56.42	52.17	5′-TGGATCAGACAACGATCGAGTGG-3′
Reverse primer	23	57.69	52.17	5′-AGTCAGGGCATAGCGCTTGTTTC-3′

Abbreviations: GAPDH, glyceraldehyde 3-phosphate dehydrogenase; MMP, matrix metalloproteinase; Tm, the melting temperature; GC, the percentage of G and C bases in primer.

Figure 1 MMP-24 expression in atherosclerotic vessels versus nonatherosclerotic vessels.

Notes: Gene expression of MMP-24 in atherosclerotic and nonatherosclerotic coronary arteries was similar in both groups (P=0.2603; U=73).
Abbreviations: MMP, matrix metalloproteinase; AV, atherosclerotic vessel; NAV, nonatherosclerotic vessel.

Figure 2 MMP-15 expression in atherosclerotic vessels versus nonatherosclerotic vessels.

Notes: Gene expression of MMP-15 showed a slight but not statistically significant increase in atherosclerotic coronary arteries (P=0.2301; U=46).
Abbreviations: MMP, matrix metalloproteinase; AV, atherosclerotic vessel; NAV, nonatherosclerotic vessel.