Observational Study to Evaluate Efficacy and Safety of Vidaslim^®, a Medical Nutrition Therapy, for Weight Loss in Subjects with Obesity

Figures & data

Box 1 Signature nutrients in Vidaslim^®

Protein* blend: whey, soy, and casein, along with all essential amino acids

Dietary fiber: polydextrose

Green tea extract: catechins

L-carnitine

White kidney bean extract: Phaseolus vulgaris extract *PDCAAS (protein digestibility–corrected amino acid score): 1

Box 2 Likert values used for each parameter

Parameter	Likert scale
Appetite	1 — very poor	2 — poor	3 — average	4 — good	5 — very good
Hunger	1 — all of the time	2 — most of the time	3 — some of the time	4 — occasionally	5 — rarely
Mood	1 — very sad,	2 — sad	3 — neither sad nor happy	4 — happy	5 — very happy
Sleep quality	1 — very poor	2 — poor	3 — average	4 — good	5 — very good
General well-being	1 — in very good spirits	2 — in good spirits mostly	3 — I have been up and down in spirits a lot	4 — in low spirits mostly	5 — in very low spirits

Table 1 Participant demography

Study completed (n)	107
Age (years)	34.09±8.26
Males/females	23/84
Weight (kg)	95.7±0.4
Mean BMI (kg/m^2)	39.3±10.5
Waist circumference (inches)	40.4±0.5
Hip circumference (inches)	41.7±6.1

Table 2 Baseline and 16-week parameters

	Baseline	16 Weeks	p-value
Weight (kg)	95.7±0.4	82.33±1.66*	0.0001
Mean BMI (kg/m^2)	39.3±10.5	33.85±8.16	0.00001
Waist circumference (inches)	40.4±0.5	36.74±5.19*	0.0001
Hip circumference (inches)	41.7±6.1	37.25±3.99*	0.0001
Heart rate (beats/min)	82.98±10.44	79.27±8.45*	0.005
Blood pressure, systolic (mmHg)	125.9±11.2	121.75±7.39*	0.002
Blood pressure, diastolic (mmHg)	81.6±7.2	80.55±7.78	0.195
Low-density lipoprotein (mg/dL)	130.8±45.9	127.90±125.713	0.201
Very low–density lipoprotein (mg/dL)	46.26±28.53	37.86±23.63	0.0186
Triglycerides (mg/dL)	186.5±67	149.97±43.23*	0.0001
Cholesterol (mg/dL)	209.2±72.1	173.75±55.93*	0.0001
Fasting blood glucose (mg/dL)	98.5±23.1	90.79±11.34*	0.0001
Postprandial blood glucose (mg/dL)	130.9±22.4	122.18±19.66	0.0241
Weight loss when breakfast replaced with Vidaslim^® (kg)	71.5±2.5	68.5±1.5	0.205
Weight loss when lunch replaced with Vidaslim (kg)	95.5±5.2	85.69±4.62*	0.0001
Weight loss when dinner replaced with Vidaslim (kg)	96.29±2.14	82.04±1.60*	0.0001

Note: *Significant (p<0.05).

Figure 1 Study flowchart.

Figure 2 Change in appetite (A), hunger (B), mood (C), sleep (D) and general well-being (E) over 16 weeks.