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Review

New horizons for multiple sclerosis therapeutics: milestones in the development of ocrelizumab

, , , &
Pages 1093-1099 | Published online: 23 Apr 2018

Figures & data

Figure 1 Representation of the three anti-CD20 monoclonal antibodies: rituximab, ocrelizumab, and ofatumumab.

Figure 1 Representation of the three anti-CD20 monoclonal antibodies: rituximab, ocrelizumab, and ofatumumab.

Figure 2 B-cell lines that are targeted and spared by the action of ocrelizumab.

Figure 2 B-cell lines that are targeted and spared by the action of ocrelizumab.

Figure 3 Mechanism of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).

Abbreviaiton: MAC, membrane attack complex.

Figure 3 Mechanism of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).Abbreviaiton: MAC, membrane attack complex.