Efficacy of twice-daily vs once-daily sessions of repetitive transcranial magnetic stimulation in the treatment of major depressive disorder: a retrospective study

Figures & data

Table 1 Demographic information and baseline test scores

	OD group, mean (SD)	TD group, mean (SD)	t/χ^2	p-value
Sex (female/male)	10/9	9/8	0.000	0.986
Age (years)	50.6 (15.5)	45.4 (14.5)	1.014	0.318
Ham-D baseline	17.3 (4.7)	18.1 (5.8)	0.531	0.599
BDI baseline	37.4 (4.7)	38.4 (10.4)	0.312	0.759
BAI baseline	26.7 (24.8)	24.8 (14.6)	0.833	0.415
PHQ baseline	17.6 (4.8)	19.7 (4.7)	1.066	0.294
SDS baseline	21.6 (6.2)	21.4 (4.7)	0.080	0.937

Abbreviations: BAI, Beck Anxiety Inventory; BDI, Beck Depression Inventory; Ham-D, Hamilton Rating Scale for Depression; OD, once-daily treatment; PHQ, Patient Health Questionnaire; SDS, Sheehan Disability Scale; TD, twice-daily treatment.

Table 2 Response rate (%) across treatment sessions

Session	10	20	30
OD (n=19)	36.8	42.1	52.6
TD (n=17)	29.4	70.6	82.4

Abbreviations: OD, once-daily treatment; TD, twice-daily treatment.

Figure 1 Change in Ham-D score throughout treatment for responders in the OD (n=11) and TD (n=14) groups.

Abbreviations: Ham-D, Hamilton Rating Scale for Depression; OD, once-daily treatment; TD, twice-daily treatment.