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Original Research

A meta-analysis of data associating DRD4 gene polymorphisms with schizophrenia

, , , &
Pages 153-164 | Published online: 03 Jan 2018

Figures & data

Figure 1 Study selection process in this meta-analysis.

Abbreviations: CNKI, China National Knowledge Infrastructure; VNTR, variable number tandem repeat.
Figure 1 Study selection process in this meta-analysis.

Table 1 Characteristics of studies that qualified to be included in the meta-analysis

Table 2 Allele frequency of 48 bp VNTR polymorphism

Table 3 Pooled associations of DRD4 polymorphisms and schizophrenia

Table 4 Subgroup associations of DRD4 polymorphisms with schizophrenia

Table 5 Genotype distribution and allele frequency of 12 bp TR

Table 6 Genotype distribution and allele frequency of 120 bp TR

Table 7 Genotype distribution and allele frequency of −521 C>T

Table 8 Genotype distribution and allele frequency of −616 C>G

Table 9 Genotype distribution and allele frequency of −376 C>T

Figure 2 Funnel plot analysis for the detection of publication bias in the association between the 48 bp VNTR (7R vs others) and schizophrenia.

Abbreviations: OR, odds ratio; 7R, 7 repeat; VNTR, variable number tandem repeat.
Figure 2 Funnel plot analysis for the detection of publication bias in the association between the 48 bp VNTR (7R vs others) and schizophrenia.

Figure 3 Funnel plot analysis for the detection of publication bias in the association between 48 bp VNTR (L vs S) and schizophrenia.

Notes: L, long allele; S, short allele.
Abbreviations: OR, odds ratio; VNTR, variable number tandem repeat.
Figure 3 Funnel plot analysis for the detection of publication bias in the association between 48 bp VNTR (L vs S) and schizophrenia.

Figure 4 Funnel plot analysis for the detection of publication bias in the association between 12 bp TR and schizophrenia.

Abbreviations: OR, odds ratio; TR, tandem repeat.
Figure 4 Funnel plot analysis for the detection of publication bias in the association between 12 bp TR and schizophrenia.

Figure 5 Funnel plot analysis for the detection of publication bias in the association between 120 bp TR and schizophrenia.

Abbreviations: OR, odds ratio; TR, tandem repeat.
Figure 5 Funnel plot analysis for the detection of publication bias in the association between 120 bp TR and schizophrenia.

Figure 6 Funnel plot analysis for the detection of publication bias in the association between −521 C>T and schizophrenia.

Abbreviation: OR, odds ratio.
Figure 6 Funnel plot analysis for the detection of publication bias in the association between −521 C>T and schizophrenia.

Figure 7 Funnel plot analysis for the detection of publication bias in the association between −616 C>G and schizophrenia.

Abbreviation: OR, odds ratio.
Figure 7 Funnel plot analysis for the detection of publication bias in the association between −616 C>G and schizophrenia.

Figure 8 Funnel plot analysis for the detection of publication bias in the association between −376 C>T and schizophrenia.

Abbreviation: OR, odds ratio.
Figure 8 Funnel plot analysis for the detection of publication bias in the association between −376 C>T and schizophrenia.