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Original Research

Relationships between clinical scales and binge eating days in adults with moderate to severe binge eating disorder in two Phase III studies

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Pages 537-546 | Published online: 15 Feb 2018

Figures & data

Figure 1 Equipercentile linking functionsa at baseline (A and B) and for change from baseline (C and D), pooled full analysis set.

Notes: aThe equipercentile linking function requires that both variables be continuous. To apply this method, scores for CGI-S, CGI-I, and Y-BOCS-BE were considered piecewise continuous ranging from X −0.5 to X +0.5, and scores for binge eating days/week were considered piecewise continuous ranging from X −0.005 to X +0.005. Therefore, all values are understood to encompass a range.
Abbreviations: BE, binge eating; CGI-I, Clinical Global Impressions–Improvement; CGI-S, Clinical Global Impressions–Severity; ET, early termination; LDX, lisdexamfetamine dimesylate; PBO, placebo; Y-BOCS-BE, Yale-Brown Obsessive Compulsive Scale modified for Binge Eating.
Figure 1 Equipercentile linking functionsa at baseline (A and B) and for change from baseline (C and D), pooled full analysis set.

Table 1 Baseline demographic and clinical characteristics, pooled full analysis set

Table 2 Binge eating days/week and Y-BOCS-BE total score distribution by CGI-Sand CGI-I scores, pooled full analysis set

Table 3 Ranges derived from the equipercentile linking function, pooled full analysis set