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Neuropsychiatric Disease and Treatment Volume 14, 2018 - Issue
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Original Research

Association between platelet distribution width and poor outcome of acute ischemic stroke after intravenous thrombolysis

Fan Gao1 Clinical Research Center, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China
,
Chen Chen2 Department of Neurology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China, [email protected]
,
Jun Lyu1 Clinical Research Center, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China
,
Jie Zheng1 Clinical Research Center, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China
,
Xian-Cang Ma1 Clinical Research Center, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China;3 Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China
,
Xing-Yun Yuan2 Department of Neurology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China, [email protected]
,
Kang Huo2 Department of Neurology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China, [email protected]
&
Jian-Feng Han2 Department of Neurology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China, [email protected]Correspondence[email protected]
 show all
Pages 2233-2239 | Published online: 03 Sep 2018

Figures & data

Table 1 Baseline characteristics and clinical features of the patients

Table 2 Clinical outcomes of patients after intravenous thrombolysis

Figure 1 Scatter plot of PDW level in different clinical outcomes.

Abbreviations: PDW, platelet distribution width; mRS, modified Rankin Scale; ENI, early neurological improvement; sICH, symptomatic intracerebral hemorrhage; ECH, extracranial hemorrhage.
Figure 1 Scatter plot of PDW level in different clinical outcomes.

Figure 2 ROC curve of PDW in predicting a poor outcome of AIS patients.

Notes: AUC: 0.689 (95% CI 0.568–0.809); p=0.005.
Abbreviations: ROC, receiver operating characteristics; PDW, platelet distribution width; AUC, area under the curve; AIS, acute ischemic stroke.
Figure 2 ROC curve of PDW in predicting a poor outcome of AIS patients.

Table 3 Multivariable logistic regression analysis for PDW of outcome after stroke

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