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Review

Neuroprogression: the hidden mechanism of depression

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Pages 2837-2845 | Published online: 30 Oct 2018

Figures & data

Figure 1 The glucocorticoids are responsible for inhibiting, by negative feedbacks, the secretion of CRF and AVP by the hypothalamus and, therefore, the secretion of ACTH by the pituitary gland.

Note: In depressed patients, this response does not function normally.
Abbreviations: ACTH, adrenocorticotropic hormone; AVP, arginine-vasopressin; CRF, corticotropin-releasing factor.
Figure 1 The glucocorticoids are responsible for inhibiting, by negative feedbacks, the secretion of CRF and AVP by the hypothalamus and, therefore, the secretion of ACTH by the pituitary gland.

Figure 2 Inhibition and synthesis of serotonin and dopamine.

Figure 2 Inhibition and synthesis of serotonin and dopamine.