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Original Research

Clinical effects of repetitive transcranial magnetic stimulation combined with atomoxetine in the treatment of attention-deficit hyperactivity disorder

Pengfei Cao1 Psychological Centre for Adolescents and Children, The Affiliated 102 Hospital of The Second Military Medical University of People’s Liberation Army of China, Shanghai, China, [email protected];2 Department of Political Affairs, College of Politics, National Defense University of People’s Liberation Army of China, Beijing, China

Jun Xing1 Psychological Centre for Adolescents and Children, The Affiliated 102 Hospital of The Second Military Medical University of People’s Liberation Army of China, Shanghai, China, [email protected]

Yin Cao3 Laboratory of Neurological Diseases, Department of Neurology, The Affiliated Changzhou No 2 People’s Hospital of Nanjing Medical University, Changzhou, China, [email protected]

Qi Cheng1 Psychological Centre for Adolescents and Children, The Affiliated 102 Hospital of The Second Military Medical University of People’s Liberation Army of China, Shanghai, China, [email protected]

Xiaojing Sun1 Psychological Centre for Adolescents and Children, The Affiliated 102 Hospital of The Second Military Medical University of People’s Liberation Army of China, Shanghai, China, [email protected]

Qi Kang1 Psychological Centre for Adolescents and Children, The Affiliated 102 Hospital of The Second Military Medical University of People’s Liberation Army of China, Shanghai, China, [email protected]

Libin Dai1 Psychological Centre for Adolescents and Children, The Affiliated 102 Hospital of The Second Military Medical University of People’s Liberation Army of China, Shanghai, China, [email protected]

Xianju Zhou3 Laboratory of Neurological Diseases, Department of Neurology, The Affiliated Changzhou No 2 People’s Hospital of Nanjing Medical University, Changzhou, China, [email protected]Correspondence[email protected]

Zixiang Song1 Psychological Centre for Adolescents and Children, The Affiliated 102 Hospital of The Second Military Medical University of People’s Liberation Army of China, Shanghai, China, [email protected]Correspondence[email protected]

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Figures & data

Table 1 General demographics of the ADHD group

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Table 2 The scores of SNAP-IV questionnaire before and after treatment in the rTMS, the ATX, and the rTMS/ATX groups

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Figure 1 The differences of SNAP-IV scores before and after treatment in the rTMS, the ATX, and the rTMS/ATX groups.

Note: *P<0.05 compared to the rTMS and the ATX groups, a repeated measure ANOVA was used.
Abbreviations: ATX, atomoxetine; NS, nonsignificant; rTMS, repetitive transcranial magnetic stimulation; SNAP-IV, the Swanson, Nolan, and Pelham, Version IV.

Table 3 The scores of cold and hot executive functions before and after the three treatments

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Figure 2 The differences of scores on cold and hot executive functions before and after treatment in the rTMS, the ATX, and the rTMS/ATX groups.

Notes: *P<0.05, compared to the rTMS group, and the ATX group; ^#P<0.05, compared to the rTMS group; a repeated measure ANOVA was used.
Abbreviations: ATX, atomoxetine; CPT, continuous performance test; IGT, Iowa Gambling Task; rTMS, repetitive transcranial magnetic stimulation.

Table 4 Correlation coefficient between age and attention deficit, hyperactivity impulse, executive function (r)

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Table 5 Correlation coefficient between attention deficit, hyperactivity impulse and CPT, arithmetic, coding, digit span (r)

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Clinical effects of repetitive transcranial magnetic stimulation combined with atomoxetine in the treatment of attention-deficit hyperactivity disorder

Table 1 General demographics of the ADHD group

Table 2 The scores of SNAP-IV questionnaire before and after treatment in the rTMS, the ATX, and the rTMS/ATX groups

Table 3 The scores of cold and hot executive functions before and after the three treatments

Table 4 Correlation coefficient between age and attention deficit, hyperactivity impulse, executive function (r)

Table 5 Correlation coefficient between attention deficit, hyperactivity impulse and CPT, arithmetic, coding, digit span (r)

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Clinical effects of repetitive transcranial magnetic stimulation combined with atomoxetine in the treatment of attention-deficit hyperactivity disorder

Figures & data

Table 1 General demographics of the ADHD group

Table 2 The scores of SNAP-IV questionnaire before and after treatment in the rTMS, the ATX, and the rTMS/ATX groups

Table 3 The scores of cold and hot executive functions before and after the three treatments

Table 4 Correlation coefficient between age and attention deficit, hyperactivity impulse, executive function (r)

Table 5 Correlation coefficient between attention deficit, hyperactivity impulse and CPT, arithmetic, coding, digit span (r)

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