Association between anxious distress in a major depressive episode and bipolarity

Figures & data

Table 1 Demographic and clinical variables in the patients with ANXD and without ANXD

Demographic and clinical variables	Without ANXD (N=33)	With ANXD (N=31)	P-value
Age (years)	52.55±14.80	56.19±15.78	0.34
Sex (M/F)	10/23	5/26	0.24
Diagnosis on admission (MDD/BD)	20/13	19/12	1.00
HRSD score on admission	17.04±8.06	24.03±8.31	0.0041a
Psychosis	5 (15.15%)	7 (22.58%)	0.53
Mixed features	4 (12.12%)	14 (45.16%)	0.0050a
Age of onset (years)	37.45±17.42	44.06±17.89	0.14
Duration of current MDE (months)	4.59±10.55	2.32±2.56	0.25
Family historya	8 (24.24%)	7 (22.58%)	1.00
Divorce history	11 (33.33%)	7 (22.58%)	0.41
Number of recurrent MDE (>2)	27 (81.82%)	22 (70.97%)	0.38
Suicide attempt	4 (12.12%)	12 (38.71%)	0.0206a
Antidepressant-induced manic episode	9 (27.27%)	11 (35.48%)	0.59
Duration of hospitalization (days)	59.15±56.01	75.35±39.17	0.19
Diagnosis on discharge (MDD/BD)	17/15	17/14	1.00

Note:

a Family history of MDD/BD in a first-degree relative.

Abbreviations: ANXD, anxious distress; BD, bipolar disorder; HRSD, Hamilton Rating Scale for Depression; MDD, major depressive disorder; MDE, major depressive episode.

Table 2 The content of prescription on discharge

Prescription on discharge	Without ANXD (N=33)	With ANXD (N=31)
Mood stabilizers	15 (45.45%)	18 (58.06%)
Antipsychotics	23 (69.70%)	15 (48.39%)
Antidepressants	19 (57.58%)	18 (58.06%)

Abbreviation: ANXD, anxious distress.