Efficacy and Safety of tDCS and tACS in Treatment of Major Depressive Disorder: A Randomized, Double-Blind, Factorial Placebo-Controlled Study Design

Figures & data

Figure 1 Study flow chart.

Table 1 The Study Measurement Schedule

	Baseline	Week 2	Week 4	Week 6
Clinical Assessment
HDRS	×	×	×	×
HAMA	×	×	×	×
MADRS	×	×	×	×
CGI	×	×	×	×
YMRS	×	×	×	×
ASRM	×	×	×	×
tDCS/tACS adverse events		×
SERS		×	×	×
Clinic lab blood	×	×	×	×
Cognitive Tests
WSCT	×	×
Stroop color-word test	×	×
Neurophysiological Measurements
EEG	×	×
fMRI	×	×

Abbreviations: HDRS, Hamilton Depression Rating Scale; HAMA, Hamilton Anxiety Rating Scale; MADRS, Montgomery-Asberg Depression Rating Scale; CGI, Clinical Global Impression; YMRS, Young Mania Rating Scale; ASRM, Altman Self-Rating Mania Scale; SERS, Asberg Side-effect Rating Scale for Antidepressant; WCST, Wisconsin Card Classification Test.