Effects of maternal psychotropic drug dosage on birth outcomes

Figures & data

Figure 1 Incidence of preterm birth for women taking or not taking medication.

Notes: Tracked line indicates population incidence of preterm birth in The Netherlands (7.7%).¹⁹ The incidence of preterm birth was 2.7% in the group without medication and 11.1% in the group with medication (P=0.18).

Table 1 Birth outcomes for women taking and not taking medication

	No medication (n=37)a		Medication (n=99)b		Total (n=136)		P
	n	%	n	%	n	%
Male infant	14	38.9	49	50.5	63	47.4	0.25
Preterm birth	1	2.7	11	11.1	12	8.8	0.18
SGA	2	5.9	3	3.2	5	3.9	0.61
Low birth weight	1	2.9	7	7.4	8	6.2	0.68
Apgar one minute ≤5	1	2.9	13	14.1	14	11.1	0.11
Apgar 5 minutes ≤7	0	0.0	15	16.3	15	11.9	0.01
	Median	Range	Median	Range	Median	Range	P
Gestational age (weeks)	39.1	26.0–42.0	39.3	24.4–42.3	39.1	24.4–42.3	0.83
Birth weight (kg)	3.3	2.0–4.2	3.4	1.2–4.6	3.4	1.5–4.6	0.30
Apgar score, one minute	9	5–10	9	1–10	9	1–10	0.13
Apgar score, 5 minutes	10	9–10	10	2–10	10	2–10	0.52

Notes:

a One sex and three birth weights and Apgar scores were missing

b two sexes, four birth weights and seven Apgar scores were missing.

Abbreviation: SGA, small for gestational age.

SuriRAltshulerLHellemannGBurtVKAquinoAMintzJEffects of antenatal depression and antidepressant treatment on gestational age at birth and risk of preterm birthAm J Psychiatry200716481206121317671283

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