Figures & data
Figure 1 Measured concentrations of serum CRTN, CK, side effect symptoms, and administered drugs for cases 1 and 2.
Notes: (A) Case 1: Measured concentrations of serum CRTN, CK (normal range of 0–160 IU/L), side effect symptoms, and administered drugs are shown. (B) Case 2: Concentrations of serum CRTN and accelerated heart rate, in addition to side effect symptoms and administered drugs, are shown. Bisoprolol fumarate, a β-adrenergic receptor antagonist metabolized by CYP2D6, was used to treat tachycardia, and neither a deterioration of depressive symptoms nor a worsening of serotonin toxicity was observed upon its administration.
Abbreviations: CRTN, creatinine; CK, creatine phosphokinase; w, week; CYP, cytochrome P450.
Abbreviations: CRTN, creatinine; CK, creatine phosphokinase; w, week; CYP, cytochrome P450.
