Figures & data
Table 1 Demographic and clinical characteristics of patients at baseline
Figure 1 Mean 17-item Hamilton Rating Scale for Depression (HAMD-17) total score during the 8-week treatment period.
![Figure 1 Mean 17-item Hamilton Rating Scale for Depression (HAMD-17) total score during the 8-week treatment period.](/cms/asset/8c573cdd-1475-4506-ba16-d0e311d765a7/dndt_a_58994_f0001_b.jpg)
Figure 2 Proportions of patients showing response to treatment (responders: HAMD-17 total score decreased by ≥50% from baseline) and remission (remitters: HAMD-17 total score <7 during the treatment period, indicating they were free from depression) during the 8-week treatment period.
![Figure 2 Proportions of patients showing response to treatment (responders: HAMD-17 total score decreased by ≥50% from baseline) and remission (remitters: HAMD-17 total score <7 during the treatment period, indicating they were free from depression) during the 8-week treatment period.](/cms/asset/0743d9d7-42b1-478b-89bb-72212b5257c4/dndt_a_58994_f0002_b.jpg)
Figure 3 Mean single Hamilton Rating Scale for Depression item scores for “work and activities” (item 7) and “psychomotor retardation” (item 8) during the 8-week treatment period.
Abbreviation: HAMD-17, 17-item Hamilton Rating Scale for Depression.
![Figure 3 Mean single Hamilton Rating Scale for Depression item scores for “work and activities” (item 7) and “psychomotor retardation” (item 8) during the 8-week treatment period.](/cms/asset/9ea3d89e-291c-4ec3-96de-3a08bb7ecb1c/dndt_a_58994_f0003_b.jpg)
Figure 4 Upper panel: frequency distribution of Clinical Global Impression Severity Scale (CGI-S) scores after 8 weeks of treatment.
![Figure 4 Upper panel: frequency distribution of Clinical Global Impression Severity Scale (CGI-S) scores after 8 weeks of treatment.](/cms/asset/a22fd1e3-9433-4436-b7fd-efd68566864f/dndt_a_58994_f0004_b.jpg)
Figure 5 Subgroup of more severely ill patients. Proportions of patients showing response to treatment (responders: HAMD-17 total score decreased by ≥50% from baseline) and remission (remitters: HAMD-17 total score <7 during the treatment period, indicating they were free from depression) in the subgroup of patients (n=3,478) with HAMD-17 total score ≥21 at baseline.
![Figure 5 Subgroup of more severely ill patients. Proportions of patients showing response to treatment (responders: HAMD-17 total score decreased by ≥50% from baseline) and remission (remitters: HAMD-17 total score <7 during the treatment period, indicating they were free from depression) in the subgroup of patients (n=3,478) with HAMD-17 total score ≥21 at baseline.](/cms/asset/017824a5-d1cf-4cd0-8c9a-d01883692ad8/dndt_a_58994_f0005_b.jpg)
Table 2 Adverse events reported by ≥0.25% of patients