Suicidal behavior among Turkish patients with Parkinson’s disease

Figures & data

Table 1 Demographic and clinical features of Parkinson’s disease (PD) patients with and without suicidal ideation

Variables	With suicidal ideation (n=14)	Without suicidal ideation (n=106)	P-values
Demographic
Sex (male/female)	10/4	68/38	0.76
Age, years*	56.7±9.9	62.2±8.8	0.06
Education, years*	5.4±1.9	8.3±3.7	<0.001
Marital status, % married	10.2	18.2	0.28
PD-related
Duration, years*	10.5±6.7	6.7±1.8	0.003
Age of PD onset, years*	46.2±6.8	55.3±9.5	<0.001
Hoehn and Yahr stage*	2.4±0.7	2.1±0.7	0.136
Schwab and England score*	74.2±13.4	81.4±9.9	0.018
UPDRS motor score*	33.4±5.7	21.3±4.8	0.003
UPDRS dyskinesia*	4.14±1.7	0.38±0.3	<0.001
UPDRS motor fluctuation score*	2.86±0.3	0.62±0.2	0.003
L-Dopa dosage, mg*	1284.29±373.8	672.4±363	0.015
Psychiatric
HDRS score*	21.3±2.6	8.7±1.6	<0.001
Presence of depression (% yes)	14 (100)	29 (27.6)	<0.001
Positive history of ICD (% yes)	10 (71.4)	18 (17.0)	<0.001
Suicide Probability Scale score*	74.7±8.4	56±14.7	<0.001

Note:

* Values presented as means ± standard deviation.

Abbreviations: UPDRS, Unified Parkinson’s Disease Rating Scale; HDRS, Hamilton Depression Rating Scale; ICD, impulse-control disorder.

Table 2 Univariate logistic regression analysis for suicidal ideation (n=14)

Variable	Odds ratio	95% CI	P-value
Age	0.76	0.76–1.13	0.51
Sex	2.60	0.66–2.69	0.07
Education	1.25	1.85–3.09	0.01
Duration of PD	2.03	1.96–4.10	0.03
UPDRS motor score	1.01	0.97–1.05	0.75
Age at PD onset	2.17	0.91–2.03	0.04
Hoehn and Yahr stage	1.45	0.64–2.37	0.28
Schwab and England score	1.97	0.93–3.01	0.27
UPDRS total score	2.31	0.63–4.20	0.65
L-Dopa dosage, mg	1.96	1.17–6.14	0.03
Depression, HDRS	5.92	2.01–4.24	0.001
History of ICD	4.97	1.90–9.38	0.002

Abbreviations: CI, confidence interval; PD, Parkinson’s disease; UPDRS, Unified Parkinson’s Disease Rating Scale; HDRS, Hamilton Depression Rating Scale; ICD, impulse-control disorder.

Table 3 Correlations between years of education, disease duration, severity of depression, and Suicide Probability Scale scores

	Suicide Probability Scale scores
	r	P
Education	0.020	0.827
Disease duration	−0.31	0.738
HDRS	0.38	0.002

Abbreviation: HDRS, Hamilton Depression Rating Scale.