Reduced serum brain-derived neurotrophic factor in patients with first onset vitiligo

Figures & data

Figure 1 The dot plot figure of BDNF in patients with vitiligo and healthy controls.

Abbreviation: BDNF, brain-derived neurotrophic factor.

Table 1 Comparison of age, sex, BAI, BDI, and serum BDNF level in subjects with vitiligo and healthy control groups

	Vitiligo (N=57)	Healthy controls (N=58)	Statistic
Age (years)	43.63±13.48	40.45±13.23	t=0.91, P=0.61
Sex, n (%)
Female	32 (55.2%)	33 (57.9%)	χ^2=0.87, P=0.85
Male	26 (44.8%)	24 (42.1%)
BAI	10.24±9.04	10.17±7.87	t=−0.46, P=0.94
BDI	11.21 ± 7.32	10.62±7.47	t=−0.38, P=0.71
BDNF level (ng/dL)	1.57±0.97	2.37±1.73	t=2.76, P =0.007

Note: Data in the Vitiligo and Healthy control columns are shown as mean ± standard deviation unless otherwise stated.

Abbreviations: BDNF, brain-derived neurotrophic factor; BAI, Beck Anxiety Inventory; BDI, Beck Depression Inventory.

Table 2 Correlation coefficients BDNF, age, BAI, BDI, DLQI, and the value of “rule of nine” in vitiligo and healthy control groups

		Age	Rule of nine	BAI	BDI	DLQI
Vitiligo	BDNF	r=−0.027 P=0.90	r=0.067 P=0.86	r=0.005 P=0.97	r=0.04 P=0.77	r=0.092 P=0.49
Healthy control	BDNF	r=−0.205 P=0.122	–	r=−0.071 P=0.59	r=0.122 P=0.36	–

Abbreviations: BDNF, brain-derived neurotrophic factor; BAI, Beck Anxiety Inventory; BDI, Beck Depression Inventory; DLQI, dermatology life quality index.