Figures & data
Table 1 Baseline characteristics
Table 2 Hypnogram parameters: night 1 and median change to night 2 (∆: night 2–night 1)
Figure 1 In some sleep parameters, age-related changes between the two nights were found.
Notes: In MS patients suffering from insomnia, younger age was correlated with an increased REM latency in the first night (A). In MS patients suffering from PLMD or RLS, older patients spent less time in REM sleep in the first night (B), whereas younger patients needed more time to fall asleep in the first night (C). Older MS patients without any sleep disorder showed a larger decrease in arousal between the first and second night, indicating possible indication for a slight FNE in older patients (D). In summary, the age-related changes were relatively small, and older and younger patients were similarly affected although in various parameters: Amongst MS patients suffering from insomnia or PLMD/RLS, the younger the patient the smaller the REM latency and sleep onset latency. In MS patients without sleep disorders, the older the patients the higher the number of arousal in the first night. But, in general, it cannot be said that older or younger patients showed a more pronounced FNE.
Abbreviations: AI, arousal index; FNE, first night effect; MS, multiple sclerosis; PLMD, periodic limb movement disorder; REM, rapid eye movement; RLS, restless legs syndrome; SOL, sleep onset latency; SRBD, sleep-related breathing disorder; TSiB, time spent in bed.
Abbreviations: AI, arousal index; FNE, first night effect; MS, multiple sclerosis; PLMD, periodic limb movement disorder; REM, rapid eye movement; RLS, restless legs syndrome; SOL, sleep onset latency; SRBD, sleep-related breathing disorder; TSiB, time spent in bed.
Table 3 Spearman’s rank correlations of the FNE with age within each subgroup
