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Nature and Science of Sleep Volume 13, 2021 - Issue
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Original Research

Effect of Interaction Between Slow Wave Sleep and Obstructive Sleep Apnea on Insulin Resistance: A Large-Scale Study

Weijun Huang1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaView further author information
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Yuenan Liu1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaView further author information
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Xiaoting Wang1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaView further author information
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Xinyi Li1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaView further author information
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Yupu Liu1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaView further author information
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Jianyin Zou1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaView further author information
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Huajun Xu1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaCorrespondence[email protected] [email protected]
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Huaming Zhu1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaView further author information
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Hongliang Yi1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-1643-1433View further author information
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Jian Guan1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaView further author information
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Shankai Yin1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China;2 Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, People’s Republic of China;3 Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, People’s Republic of ChinaView further author information
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Pages 739-749 | Published online: 04 Jun 2021

Figures & data

Table 1 Clinical and Sleep Characteristics of Subjects Stratified by OSA Severity Categories

Table 2 Clinical and Sleep Characteristics of OSA Patients (n=5709) Stratified by SWS Categories

Table 3 Adjusted ORs and 95% CIs for the Associations of IR with OSA (PS as the Reference), SWS (SWS > 22.1% as the Reference) and Their Joint Effects (PS as Reference)

Table 4 Adjusted ORs and 95% CIs for the Association Between SWS and IR in OSA (SWS > 21.3% as the Reference) and PS Groups (SWS > 24.7% as the Reference)

Table 5 Adjusted ORs and 95% CIs of IR Associated with SWS in Analyses Stratified by OSA Severity

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