362
Views
1
CrossRef citations to date
0
Altmetric
SHORT REPORT

Correlation Analysis Between Disease Activity and Anxiety, Depression, Sleep Disturbance, and Quality of Life in Patients with Inflammatory Bowel Disease

, , , , , , , , , , , & ORCID Icon show all
Pages 407-421 | Received 06 Feb 2023, Accepted 17 May 2023, Published online: 26 May 2023

Figures & data

Table 1 General Clinical Features with Remission and Activity in Patients of Inflammatory Bowel Disease

Table 2 Anxiety, Depression, Sleep Quality, and Quality of Life in IBD Patients in Activity Compared with in Remission

Table 3 Anxiety, Depression, Sleep Quality, and Quality of Life in IBD Patients in Mild, Moderate, Severe Activity

Figure 1 Proportions of anxiety (A), depression (B), sleep disturbance (C) and poor quality of life (D) in IBD patients with different disease activity (***P<0.001, **P<0.01, *P<0.05).

Abbreviations: IBD, inflammatory bowel disease; UC, ulcerative colitis; CD, Crohn’s disease.
Figure 1 Proportions of anxiety (A), depression (B), sleep disturbance (C) and poor quality of life (D) in IBD patients with different disease activity (***P<0.001, **P<0.01, *P<0.05).

Figure 2 Proportions of anxiety (A), depression (B), sleep disturbance (C) and poor quality of life (D) in patients with mild, moderate and moderately active IBD (***P<0.001, *P<0.05).

Abbreviations: IBD, inflammatory bowel disease; UC, ulcerative colitis; CD, Crohn’s disease.
Figure 2 Proportions of anxiety (A), depression (B), sleep disturbance (C) and poor quality of life (D) in patients with mild, moderate and moderately active IBD (***P<0.001, *P<0.05).

Figure 3 Venn diagram of comorbid anxiety, depression, sleep disturbance and poor quality of life in IBD patients with different disease activity (A): active stage, (B): remission stage, (C): mild activity, (D): moderate activity, (E): severe activity.

Abbreviation: IBD, inflammatory bowel disease.
Figure 3 Venn diagram of comorbid anxiety, depression, sleep disturbance and poor quality of life in IBD patients with different disease activity (A): active stage, (B): remission stage, (C): mild activity, (D): moderate activity, (E): severe activity.

Table 4 Scores of GAD-7, PHQ-9, PSQI, and IBD-Q in IBD Patients in Activity Compared with in Remission (Scores, )

Table 5 Scores of GAD-7, PHQ-9, PSQI, and IBD-Q in IBD Patients in Mild, Moderate, Severe Activity (Scores, )

Table 6 Scores of Patients with IBD in Active versus Remission When Combined with One (Anxiety, Depression or Sleep Disturbance), Two (Anxiety + Depression, Anxiety + Sleep Disturbance, Depression + Sleep Disturbance) or Three (Anxiety + Depression + Sleep Disturbance) (Scores, )

Figure 4 GAD-7 score (A), PHQ-9 score (B), PSQI score (C), and IBD-Q score (D) in IBD patients with different disease activity (***P<0.001, **P<0.01, *P<0.05).

Abbreviations: IBD, inflammatory bowel disease; UC, ulcerative colitis; CD, Crohn’s disease; GAD-7, Generalized Anxiety Disorder 7-item Scale; PHQ-9, Patient Health Questionnaire-9; PSQI, Pittsburgh Sleep Quality Index; IBD-Q; Inflammatory Bowel Disease Quality-of-Life Questionnaire.
Figure 4 GAD-7 score (A), PHQ-9 score (B), PSQI score (C), and IBD-Q score (D) in IBD patients with different disease activity (***P<0.001, **P<0.01, *P<0.05).

Data Sharing Statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.