Investigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and B-scan ultrasound

Figures & data

Figure 1 (A) Fundoscopy image of ocular melanoma; (B) measurements of height and maximum base diameter for choroidal melanoma on ultrasound scan.

Figure 2 (A) Characteristic homogeneous appearance of choroidal melanoma on ultrasound scans; (B) application of Doppler technique depicting and enabling the study of tumor’s neovascularization.

Figure 3 Characteristic appearance of choroidal melanoma on MRI.

Notes: (A) High intensity signal on T1-weighted images, compared with the vitreous body; (B) low intensity signal on T2-weighted images; (C) arterial enhancement on T1-weighted images, after an intravenous bolus administration of paramagnetic contrast agent; (D) appearance on coronal plane; (E) sagittal plane on T1-weighted images, after an intravenous bolus administration of paramagnetic contrast agent; (F) T1-weighted sequence using fat suppression technique, after an intravenous bolus administration of paramagnetic contrast agent.
Abbreviation: MRI, magnetic resonance imaging.

Figure 4 Homogeneity incidence detected by using different methods.

Abbreviations: GD, gadolinium; MRI, magnetic resonance imaging.

Figure 5 Number of cases where retinal detachment was detected by using different methods.

Abbreviations: GD, gadolinium; MRI, magnetic resonance imaging.

Figure 6 Imaging of choroidal melanoma on MRI and ultrasound scan.

Notes: (A) Tumor showing high intensity signal on T1-weighted images. Its heterogeneous appearance accounts to the melanin distribution pattern. A small retinal detachment may be depicted; (B) T1-weighted image on a coronal plane; (C) heterogeneous appearance and low intensity signal on T2-weighted images for the choroidal melanoma. The retinal detachment is apparent; (D) tumor showing homogeneous arterial enhancement on T1-weighted images with fat suppression, after an intravenous bolus administration of paramagnetic contrast agent. The retinal detachment is shown; (E) T1-weighted image with fat suppression, after an intravenous bolus administration of paramagnetic contrast agent on a sagittal plane; (F) for the same patient, the small retinal detachment is noted on ultrasound scan.
Abbreviation: MRI, magnetic resonance imaging.

Figure 7 Choroidal melanoma on MRI and ultrasound scan.

Notes: (A) Homogeneous intraocular mass showing high intensity signal on T1-weighted images; (B) on T2-weighted images, it shows low intensity signal; (C) the tumor showing heterogeneous arterial enhancement on T1-weighted images with fat suppression, after an intravenous bolus administration of paramagnetic contrast agent; (D) T1-weighted image with fat suppression, after an intravenous bolus administration of paramagnetic contrast agent on a coronal plane; (E) for the same patient, ultrasound scan revealed a retinal detachment which is undetected by the MRI.
Abbreviation: MRI, magnetic resonance imaging.

Figure 8 Arterial enhancement of choroidal melanoma on MRI scan enabling imaging differentiation between the tumor and retinal detachment.

Notes: (A) Before an intravenous bolus administration of paramagnetic contrast agent; (B) after an intravenous bolus administration of paramagnetic contrast agent.
Abbreviation: MRI, magnetic resonance imaging.