Is high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?

Figures & data

Table 1 Clinical features in the non-myopic group and highly myopic group

	Non-myopic group	Highly myopic group	P-value
	AL <24.0 mm	AL ≥26.5 mm
	93 eyes	53 eyes
Age at first visit (years)			<0.0001
Mean ± SD	62.6±10.2	51.1±9.9
Range	27–85	28–74
Sex (male/female)	36/57	40/13	<0.0001
Refractive error (D)			<0.0001
Mean ± SD	−0.0±1.4	−8.6±2.8
Range	3.25 to −5.5	−3.5 to −16.5
Axial length (mm)			<0.0001
Mean ± SD	23.0±0.7	27.6±1.0
Range	21.39–23.99	26.50–31.73
Follow-up period (years)			0.0406
Mean ± SD	12.2±4.0	10.6±4.1
Range	5.2–21.2	5.5–18.7
Baseline IOP (mmHg)			0.0636
Mean ± SD	16.3±4.5	17.8±4.8
Range	9–32	10.3–35
Follow-up IOP (mmHg)			0.0009
Mean ± SD	12.8±2.5	13.8±2.3
Range	8.5–26.9	7.2–20.4
IOP reduction (%)			0.8823
Mean ± SD	17.7±16.1	18.7±16.8
Range	−32–49	−18–79
IOP fluctuation (mmHg)			0.0099
Mean ± SD	7.6±3.2	6.2±1.6
Range	3–20	3–12
Central corneal thickness (μm)			0.4029
Mean ± SD	538.7±35.0	546.3±37.1
Range	441–614	438–644
Number of visual field tests			0.0171
Mean ± SD	24.0±8.7	20.5±7.3
Range	9–48	9–36
Baseline MD (dB)			0.2229
Mean ± SD	−6.12±5.14	−7.72±6.21
Range	1.51 to −26.66	−0.05 to −21.22
Final MD (dB)			0.9919
Mean ± SD	−10.22±7.33	−10.29±7.42
Range	0.88 to −29.92	−0.30 to −26.34
MD slope (dB/year)			0.0183
Mean ± SD	−0.383±0.547	−0.192±0.275
Range	0.35 to −3.65	0.33 to −0.93
DH number			0.0311
Mean ± SD	1.60±3.04	0.93±2.13
Range	0–19	0–12

Abbreviations: AL, axial length; D, diopters; IOP, intraocular pressure; MD, mean deviation; dB, decibel; DH, disk hemorrhage.

Figure 1 The cumulative probability of non-progression of VF loss in the highly myopic group and the non-myopic group.

Notes: The cumulative probability of non-progression of VF loss was significantly greater in the highly myopic group (10-year survival rate, 73.7%±6.8%) than in the non-myopic group (10-year survival rate, 46.3%±5.8%; log-rank test, P=0.0142).
Abbreviation: VF, visual field.

Figure 2 The cumulative probability of occurrence of DH in the highly myopic group and the non-myopic group.

Notes: The cumulative probability of DH incidences was significantly greater in the non-myopic group (10-year survival rate, 47.2%±6.6%) than in the highly myopic group (10-year survival rate, 26.4%±5.4%; log-rank test, P=0.0413).
Abbreviation: DH, disk hemorrhage.