Satisfaction and convenience of using terpenoid-impregnated eyelid wipes and teaching method in people without blepharitis

Figures & data

Table 1 Demographic and clinical characteristics of the participants

Demographic and clinical characteristics	Total (n=50)	Video* (n=25)	Live** (n=25)	p-value
Demographics
Gender
Female, n (%)	44 (88.0)	22 (88.0)	22 (88.0)	1.000
Age, mean ± SD	42.7±16.5	40.2±15.8	45.1±17.2	0.298
Ethnicity
Chinese, n (%)	46 (92.0)	23 (92.0)	23 (92.0)	0.261
Socioeconomic indicators
Highest education
Up to A levels/diploma, n (%)	33 (66.0)	18 (72.0)	15 (60.0)
University and above, n (%)	17 (34.0)	7 (28.0)	10 (40.0)	0.551
Housing type
≤4 rooms, n (%)	21 (42.0)	8 (32.0)	13 (52.0)
5 room/executive, n (%)	25 (50.0)	14 (56.0)	11 (44.0)
Private, n (%)	4 (8.0)	3 (12.0)	1 (4.0)	0.279
Gross income
≤S$3,000, n (%)	30 (60.0)	15 (60.0)	15 (60.0)
>S$3,000, n (%)	10 (40.0)	10 (40.0)	20 (40.0)	1.000
Clinical characteristics
SPEED score, mean ± SD	7.6±5.7	7.2±5.3	8.0±6.2	0.624
Presence of crusting RE, n (%)***	5 (10.0)	1 (4.0)	4 (16.0)	0.157
Presence of meibomian gland plaque RE, n (%)***	18 (36.0)	9 (36.0)	9 (36.0)	1.000
Regularity of meibomian gland orifice RE, n (%)***	45 (90.0)	24 (96.0)	21 (84.0)	0.157

Notes:

* These participants were given a link to an online video demonstration of the eyelid wipe technique.

** These participants were given a live demonstration of the eyelid wipe technique.

*** Baseline clinical characteristics of both eyes were taken but only the right eye characteristics were presented, as there is a significant correlation (based on Pearson correlation coefficient) between right and left eyes for the presence of crusting, plaque, or regularity (R>0.6, p<0.01).

Abbreviations: RE, right Eye; S$, Singapore dollars; SPEED, Standard Patient Evaluation Eye Dryness.

Figure 1 The overall frequency of ease, comfort, convenience, and stinging experienced by participants. (A) Ease levels, (B) comfort levels, (C) convenience levels, and (D) stinging levels.

Table 2 Competence of use assessed by investigator, ease, comfort, convenience, and stinging experienced by participants

Factors affecting acceptability of Cliradex	Total (n=50)	Video* (n=25)	Live** (n=25)	p-value***
Acceptability of Cliradex – ease of use
Median (lower quartile, median, upper quartile)	5 (4,5,6)	5 (4,5,6)	5 (4,5,6)
Easy to extremely easy (grades 4–6), n (%)	47 (94.0)	25 (100.0)	22 (88.0)
Extremely difficult to difficult (grades 1–3), n (%)	3 (6.0)	0 (0.0)	3 (12.0)	0.235
Acceptability of Cliradex – comfort level
Median (lower quartile, median, upper quartile)	4 (3,4,5)	4 (3,4,5)	3 (3,3,4)
Slightly comfortable to extremely comfortable (grades 4–6), n (%)	26 (52.0)	16 (64.0)	10 (40.0)
Extremely uncomfortable to slightly uncomfortable (grades 1–3), n (%)	24 (48.0)	9 (36.0)	15 (60.0)	0.156
Acceptability of Cliradex – convenience
Median (lower quartile, median, upper quartile)	5 (4,5,5)	5 (5,5,5)	5 (4,5,6)
Convenient to extremely convenient (grades 4–6), n (%)	45 (90.0)	24 (96.0)	21 (84.0)
Extremely inconvenient to inconvenient (grades 1–3), n (%)	5 (10.0)	1 (4.0)	4 (16.0)	0.349
Acceptability of Cliradex – stinging
Median (lower quartile, median, upper quartile)	2 (2,2,3)	2 (2,2,3)	3 (2,3,3)
Little/no stinging, to some but mild stinging (grade 1–2), n (%)	26 (52.0)	14 (56.0)	12 (48.0)
Quite bad stinging but goes away, to untolerable stinging (grade 3–4), n (%)	24 (48.0)	11 (44.0)	13 (52.0)	0.473
Competence of use
Median (lower quartile, median, upper quartile)	4 (3,4,4)	3 (3,3,4)	4 (3,4,4)
Reasonable to excellent performance (grade 3–4), n (%)	42 (84.0)	20 (80.0)	22 (88.0)
Unable to perform, to needs improvement (grade 1–2), n (%)	8 (16.0)	5 (20.0)	3 (12.0)	0.70

Notes:

* These participants were given a link to an online video demonstration of the eyelid wipe technique.

** These participants were given a live demonstration of the eyelid wipe technique.

*** For comparing medians, Mann–Whitney U test was used, and for comparing proportions in 2×2 contingency tables, the chi square test and Fisher’s exact test were used. Cliradex^® lid wipes (Bio-Tissue, Doral, FL, USA).