Reference values for anterior chamber morphometrics with swept-source optical coherence tomography in a Caucasian population

Figures & data

Figure 1 Location of TIA, ACD and LV is shown in an SS-OCT image. The ICA tool is shown which had to be placed manually on the scleral spur by the operator which then displayed the lines measuring the anterior chamber morphometric data displayed in the tables. (A) An open anterior chamber. (B) Angle closure with shallow ACD. In both images, TIA is displayed in green, ACD in blue and LV in pink.

Abbreviations: TIA, trabecular iris angle; ACD, anterior chamber depth; LV, lens vault; SS-OCT, swept-source optical coherence tomography; ICA, iridocorneal angle; SS, scleral spur; AR, angle recess; N, nasal; T, temporal.

Figure 2 Distribution of the (A) TIA500, (B) ACD and (C) LV on the right phakic eyes.

Abbreviations: TIA, trabecular iris angle at 500 µm; ACD, anterior chamber depth; LV, lens vault.

Figure 3 Flowchart of inclusion and exclusion of study participants.

Abbreviation: SS-OCT, swept-source optical coherence tomography.

Table 1 Temporal TIA500 in the right phakic eyes (SS-OCT)

	N (%)	TIA500 (degrees)							P-value
		Mean	SD	Range	5th percentile	10th percentile	20th percentile	90th percentile
Gender									0.015
Male	294 (45.4)	28.30	11.40	0.0–62.6	10.3	14.0	17.8	43.6
Female	353 (54.6)	25.98	12.46	0.0–67.8	5.8	11.0	14.9	43.1
Age group (years)									0.81
40–49	102 (15.8)	27.60	12.20	0.0–62.1	8.8	13.1	17.1	43.2
50–59	160 (24.7)	27.18	12.33	0.0–63.1	4.9	11.2	17.0	42.9
60–69	213 (32.9)	27.27	11.32	0.0–67.8	10.8	14.0	17.0	44.3
70–79	172 (26.6)	26.30	12.58	0.0–62.6	5.2	10.3	15.2	42.7
Refractive error									<0.01
Myopia	182 (28.1)	32.17	11.34	2.7–67.8	13.2	17.4	23.7	45.6
Emmetropia	228 (35.2)	25.92	11.98	0.0–63.1	6.4	11.6	16.6	41.7
Hyperopia	154 (23.8)	22.71	10.69	0.0–55.7	4.9	10.7	13.9	37.6
Total	647 (100)	27.04	12.04	0.0–67.8	8.8	12.5	16.8	43.8

Note: Refractive error (SE) was defined as follows: myopia as mean SE ≤−1 D, emmetropia as mean SE ≤1 D and >−1 D and hyperopia as mean SE >1 D.

Abbreviations: TIA500, trabecular iris angle at 500 µm; SS-OCT, swept-source optical coherence tomography; SD, standard deviation; SE, spherical equivalent.

Table 2 Nasal TIA500 in the right phakic eyes (SS-OCT)

	N (%)	TIA500 (degrees)							P-value
		Mean	SD	Range	5th percentile	10th percentile	20th percentile	90th percentile
Gender									0.14
Male	294 (45.4)	28.17	11.62	0.0–60.2	9.9	13.3	18.0	43.3
Female	353 (54.6)	26.80	11.84	0.0–62.0	8.3	12.2	16.2	40.8
Age group (years)									0.20
40–49	102 (15.8)	28.24	11.18	0.0–52.5	12.6	14.5	17.7	42.4
50–59	160 (24.7)	27.95	12.14	0.0–62.0	7.7	13.4	18.7	43.2
60–69	213 (32.9)	27.97	11.46	0.0–60.2	10.6	13.1	17.3	43.2
70–79	172 (26.6)	25.79	12.02	0.0–62.0	5.9	10.3	15.2	39.5
Refractive error									<0.01
Myopia	182 (28.1)	32.47	11.18	1.5–60.2	14.0	18.4	23.4	47.3
Emmetropia	228 (35.2)	26.54	11.36	0.0–62.0	7.7	11.7	16.3	40.0
Hyperopia	154 (23.8)	22.90	10.59	0.0–58.5	7.0	10.1	13.3	36.9
Total	647 (100)	27.43	11.75	0.0–62.0	9.0	12.7	17.3	42.7

Note: Refractive error (SE) was defined as follows: myopia as mean SE ≤−1 D, emmetropia as mean SE ≤1 D and >−1 D and hyperopia as mean SE >1 D.

Abbreviations: TIA500, trabecular iris angle at 500 µm; SS-OCT, swept-source optical coherence tomography; SD, standard deviation; SE, spherical equivalent.

Table 3 ACD in the right phakic eyes (SS-OCT)

	N (%)	ACD (mm)							P-value
		Mean	SD	Range	5th percentile	10th percentile	20th percentile	90th percentile
Gender									<0.01
Male	294 (45.4)	2.80	0.37	1.63–3.93	2.13	2.30	2.50	3.25
Female	353 (54.6)	2.70	0.37	1.58–3.70	2.10	2.23	2.42	3.20
Age group (years)									0.01
40–49	102 (15.8)	2.83	0.34	1.92–3.55	2.29	2.41	2.52	3.29
50–59	160 (24.7)	2.79	0.30	1.73–3.68	2.17	2.31	2.47	3.30
60–69	213 (32.9)	2.76	0.37	1.81–3.70	2.15	2.27	2.45	3.23
70–79	172 (26.6)	2.65	0.38	1.58–3.93	2.03	2.14	2.34	3.10
Refractive error									0.01
Myopia	182 (28.1)	2.92	0.34	1.98–3.93	2.40	2.45	2.62	3.33
Emmetropia	228 (35.2)	2.72	0.36	1.58–3.70	2.08	2.27	2.47	3.21
Hyperopia	154 (23.8)	2.59	0.35	1.63–3.57	2.02	2.15	2.26	3.03
Total	647 (100)	2.75	0.37	1.58–3.93	2.13	2.27	2.45	3.23

Note: Refractive error (SE) was defined as follows: myopia as mean SE ≤−1 D, emmetropia as mean SE ≤1 D and >−1 D and hyperopia as mean SE >1 D.

Abbreviations: ACD, anterior chamber depth; SS-OCT, swept-source optical coherence tomography; SD, standard deviation; SE, spherical equivalent.

Table 4 LV in the right phakic eyes (SS-OCT)

	N (%)	LV (mm)							P-value
		Mean	SD	Range	10th percentile	80th percentile	90th percentile	95th percentile
Gender									0.02
Male	294 (45.4)	0.41	0.31	−0.43 to 1.49	0.02	0.65	0.80	0.90
Female	353 (54.6)	0.46	0.30	−0.20 to 1.52	0.06	0.71	0.87	0.95
Age group (years)									<0.01
40–49	102 (15.8)	0.34	0.27	−0.43 to 1.03	−0.01	0.61	0.71	0.74
50–59	160 (24.7)	0.39	0.30	−0.42 to 1.24	0.02	0.62	0.81	0.90
60–69	213 (32.9)	0.43	0.29	−0.30 to 1.49	0.06	0.68	0.80	0.90
70–79	172 (26.6)	0.54	0.30	−0.23 to 1.52	0.21	0.80	0.93	1.03
Refractive error									<0.01
Myopia	182 (28.1)	0.30	0.28	−0.43 to 1.15	−0.06	0.52	0.69	0.76
Emmetropia	228 (35.2)	0.45	0.30	−0.42 to 1.52	0.07	0.69	0.83	0.93
Hyperopia	154 (23.8)	0.58	0.27	−0.23 to 1.31	0.24	0.80	0.92	0.99
Total	647 (100)	0.44	0.30	−0.43 to 1.52	0.05	0.69	0.83	0.93

Note: Refractive error (SE) was defined as follows: myopia as mean SE ≤−1 D, emmetropia as mean SE ≤1 D and >−1 D and hyperopia as mean SE >1 D.

Abbreviations: LV, lens vault; SS-OCT, swept-source optical coherence tomography; SD, standard deviation; SE, spherical equivalent.