Effect of phenylephrine/ketorolac on iris fixation ring use and surgical times in patients at risk of intraoperative miosis

Figures & data

Table 1 Patient demographic characteristics

	Phenylephrine/ketorolac (n=10)	Epinephrine (n=36)	p-value
Age (years), mean (range), median	75.7 (66–85), 77	79.1 (57–95), 81.5	0.0848a
Male, n (%)	5 (50)	17 (47)	1.000b
Axial length (mm), mean (SD)	23.26 (0.86)	23.51 (0.98)	0.497a
Alpha-1 antagonist use, n (%)	0	6 (17)	0.315b

Notes:

a Wilcoxon rank-sum test.

b Fisher’s exact test.

Table 2 Surgical characteristics by treatment group

	Phenylephrine/ketorolac (n=10)	Epinephrine (n=36)	p-value
Ring use, n (%)	0	18 (50)	0.0034a
Surgical time (minutes), mean (range), median	10.1 (8–13), 10	14.3 (7–39), 13	0.0068b

Notes:

a Fisher’s exact test.

b Wilcoxon rank-sum test.

Figure 1 Mean surgical times for the group receiving phenylephrine/ketorolac, epinephrine without an iris fixation ring, and epinephrine with an iris fixation ring.

Notes: No phenylephrine/ketorolac-treated patients required an iris fixation ring. Significance was tested with a Wilcoxon rank-sum test using the Bonferroni method to correct for multiple comparisons.