Figures & data
Table 1 Baseline demographic and clinical characteristics of 89 patients with neovascular glaucoma
Figure 1 Preoperative and postoperative clinical outcomes comparing trabeculectomy alone and EX-PRESS implantation.
Notes: (A) Mean IOP was significantly reduced in both groups before and after surgery. At week 1, IOP was significantly lower in the Trab group than in the EX group (P=0.045). (B) Visual acuity (logMAR) after EX-PRESS implantation and trabeculectomy alone. There was no significant difference at any time point between the two groups. (C) Mean number of antiglaucoma medications was significantly lower before and after surgery in both groups. There were no significant differences between the groups at baseline and at the final visit time points. The data are expressed as mean ± SD. (D) Kaplan–Meier survival analysis after EX-PRESS implantation versus trabeculectomy alone. Success was defined as 5 mmHg ≤ IOP ≤21 mmHg, with or without medications. Failure was defined as follows: two consecutive IOP measurements outside the above-mentioned range 2 weeks after glaucoma surgery, repeat glaucoma surgery, or worsening of best-corrected visual acuity to no light perception. Survival rate did not differ significantly between the two groups (P=0.51). *P<0.05.
Abbreviations: D, day; EX, EX-PRESS implantation; IOP, intraocular pressure; logMAR, logarithm of the minimum angle of resolution; M, month; Trab, trabeculectomy alone; W, week.
Abbreviations: D, day; EX, EX-PRESS implantation; IOP, intraocular pressure; logMAR, logarithm of the minimum angle of resolution; M, month; Trab, trabeculectomy alone; W, week.
Table 2 Postoperative complications after trabeculectomy alone and after EX-PRESS implantation in patients with neovascular glaucoma
Table 3 Additional surgical treatment after trabeculectomy alone and after EX-PRESS implantation in patients with neovascular glaucoma
Figure 2 Kaplan–Meier survival analysis of surgical outcomes in eyes that underwent EX-PRESS implantation for neovascular glaucoma.
Notes: (A) With a history of previous vitrectomy (n=15) versus without a history of previous vitrectomy (n=35; P=0.047). (B) With intravitreal bevacizumab (<1 month; n=9) versus without intravitreal bevacizumab (n=21; P=0.91). (C) Age <60 years (n=19) versus age ≥60 years (n=31; P=0.13). (D) Combined cataract surgery (n=12) versus only EX-PRESS implantation (n=38; P=0.093). *P<0.05.
Abbreviation: IVB, intravitreal bevacizumab.
Abbreviation: IVB, intravitreal bevacizumab.
Table 4 Potential predictors of surgical success in patients with neovascular glaucoma who underwent EX-PRESS implantation