Figures & data
Figure 1 Temporal kinetics of ketorolac concentrations (±SE M) following a single topical administration of the CMC-containing 0.45% ketorolac, pH 6.8 (Acuvail), and the 0.4% ketorolac, pH 7.4 (Acular LS), in aqueous humor (a) and iris-ciliary body (b).
Table 1 Aqueous Humor pharmacokinetics of ketorolac following administration of the 0.4% ketorolac, pH 7.4 (Acular LS), and the CMC-containing 0.45% ketorolac, pH 6.8 (Acuvail), formulations at varying pH
Table 2 Pharmacokinetics of ketorolac in iris-ciliary body following administrations of the CMC-containing 0.45% ketorolac, pH 6.8 (Acuvail), and the 0.4% ketorolac, pH 7.4 (Acular LS)
Figure 2 Simulation of ketorolac concentrations in iris-ciliary body following multiple topical administrations of the CMC-containing 0.45% ketorolac, pH 6.8 (Acuvail), and the 0.4% ketorolac, pH 7.4 (Acular LS).
