Retinal detachment in albinism

Figures & data

Table 1 Clinical characteristics of retinal detachment in albinism case series

Patient	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Age (years)	38	42	13	18	12	29	51	29	54	59	35	59	61	42	42	30	33
Sex	F	M	M	F	M	M	M	M	M	F	M	M	M	M	M	F	M
Race	I	I	I	I	I	I	A	C	C	C	C	A	C	C	C	C	C
OD/OS	OS	OS	OS	OS	OS	OD	OS	OS	OD	OD	OS	OS	OS	OD	OS	OS	ND
Initial vision	20/317	CF15 cm	20/100	CF2m	20/500	20/500	20/200	20/200	CF4m	HM	LP	HM	20/40	CF5 cm	CF10 cm	CFNF	CFNF
RD location	Superior	Inferior	Inferior	Total	Total	Total	Superior + temporal	Nasal	Inferior	Inferior	Total	Inferior	Supero temporal	Total	Total	Total	Superior
Macula off	Off	Off	Off	Off	Off	Off	Off	On	On	On	On	Off	On	On	On	On	On
Tear number and location	Superior round holes; lattice	HST superotemporal	Dialysis infero temporal	HST temporal; lattice	HST superior	HST superior	Can’t find	HST nasal	2 HST	HST inferior	Giant tear	HST inferonasal; lattice	Dialysis superior	2 HST superior; lattice	Diffuse lattice	Giant tear	HST supero temporal
PVR grade at presentation	No	No	A	No	No	No	B	No	No	No	CA	A	No	No	No	CA	No
Nystagmus severity	No	No	No	No	No	No	No	Mild	Moderate	No	Moderate	Moderate	Mild	Moderate	Moderate	Severe	Moderate
High myopia (<−6 diopters)	No	Yes	No	No	No	No	No	No	No	Yes	No	Yes	No	Yes	Yes	Yes	Yes
Initial surgery	SB	PPV	SB	SB	SB	SB	PPV	SB	PPVSB	PPVSB	Phaco PPV	PPV	Laser	SBPPV	SB	SB	Laser
Total number of eye surgeries	1	3	1	1	1	4	1	1	2	1	2	1	3	1	1	5	2
SB	Yes	No	Yes	Yes	Yes	Yes	No	Yes	Yes	Yes	No	No	Yes	Yes	Yes	Yes	No
PPV	No	Yes	No	No	No	No	PPV	No	Yes	Yes	Yes	Yes	No	Yes	No	Yes	Yes
C3F8	No	No	No	No	No	No	No	No	No	No	No	Yes	Yes	No	No	No	Yes
Silicone oil	No	Yes	No	No	No	No	No	No	Yes	Yes	Yes	No	No	Yes	No	Yes	No
Endolaser	No	Yes	No	No	No	No	Yes	No	Yes	Yes	Yes	No	No	No	No	No	No
Cryopexy	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes	Yes	No	Yes	Yes	Yes	Yes	Yes	Yes
Follow-up	3 m	3 y	1 m	10 m	1 m	12 m	12 m	12 m	72 m	11 m	12 m	12 m	8 y	8 y	45 y	28 y	12 m
Final vision	20/200	20/200	20/80	20/120	20/159	20/30	20/200	20/200	CF4m	20/400	LP	20/150	20/60	LP	CF10cm	HM from severe PCO	20/400
Additional surgeries	No	SO exchange, endolaser, cryopexy, retinotomy (2 m after first surgery); SO exchange and endolaser (18 m after first surgery)	No	No	No	PPV, endolaser, SO injection 1 month after first surgery; SO removal (6 m after first surgery); trabeculectomy (36 m after first surgery)	Retinotomy	No	SO removal then SO injection	SB	SO exchange with retinotomy	No	Cryopexy then 7 m later SB, cryopexy, gas	No	No	Phaco withimplant	PPV

Abbreviations: RD, retinal detachment; PVR, proliferative vitreoretinopathy; m, months; y, years; HST, horseshoe tear; PPV, pars plana vitrectomy; SB, scleral buckle; LP, light perception; HM, hand motion; CF, counting finger; phaco, phacoemulsification; SO, silicone oil; OD, right eye; OS, left eye; M, male; F, female; I, Indian; C, Caucasian; A, Asian; ND, not determined; PCO, posterior capsular opacification.

Figure 1 Flow chart of the pathophysiology of retinal detachment in albinos.

Abbreviation: RPE, retinal pigment epithelium.