Corneal imaging and densitometry measurements in keratoconus patients to monitor disease progression and treatment outcomes after contact lens or Intacs treatment

Figures & data

Table 1 Mean and SD for corneal densitometry at pre treatment and post treatment for the CL group

Zone (mm)	Layers	Pre treatment, mean (SD)	Post treatment, mean (SD)	P-value
0–2	Anterior	20.6 (1.78)	21.2 (1.6)	0.03a
	Central	17.6 (1.7)	17.2 (1.09)	0.27
	Posterior	12.9 (1.07)	12.5 (1.1)	0.19
2–6	Anterior	17.96 (1.04)	18.24 (1.1)	0.19
	Central	15.07 (0.98)	15.1 (0.63)	0.82
	Posterior	11.8 (0.88)	11.9 (0.48)	0.65
6–10	Anterior	18.27 (2.3)	17.83 (1.95)	0.4
	Central	15.3 (2.1)	15.7 (2.3)	0.4
	Posterior	12.95 (2.06)	12.97 (2.01)	0.96

Note:

a Significance at P-value of <0.05.

Abbreviation: SD, standard deviation.

Table 2 Mean and SD for corneal densitometry at pre treatment and post treatment for the Intacs group

Zone (mm)	Layers	Pre treatment, mean (SD)	Post treatment, mean (SD)	P-value
0–2	Anterior	25.02 (3.23)	23.14 (3.9)	0.06
	Central	19.47 (3.3)	17.03 (4.4)	0.13
	Posterior	14.40 (2.78)	12.31 (3.36)	0.09
2–6	Anterior	21.48 (2.89)	22.10 (5.1)	0.59
	Central	16.6 (2.9)	17.95 (5.07)	0.50
	Posterior	13.81 (1.9)	15.27 (4.9)	0.40
6–10	Anterior	19.27 (2.3)	18.88 (5.59)	0.80
	Central	15.14 (2.43)	15.32 (5.32)	0.92
	Posterior	13.63 (2.05)	13.10 (4.38)	0.69

Abbreviation: SD, standard deviation.

Figure 1 A comparison of the pre treatment and post treatment corneal densitometry for both groups at different corneal zones and layers.

Notes: *Significant at P-value of <0.05. **Significant at P-value of <0.01.
Abbreviations: GSU, grayscale unit; CL, contact lens.

Table 3 Mean and SD for corneal thickness at pre treatment and post treatment at 12 months for CL and Intacs groups

	Treatment type	Pre treatment, mean (SD)	Post treatment, mean (SD)	P-value
CCT	CL	502 (48.5)	488 (47.7)	0.02
	Intacs	457.5 (32.1)	449.4 (31.0)	0.27
Thinnest area	CL	478 (54.2)	468.6 (45.7)	0.04
	Intacs	430.4 (39.8)	425.2 (39.9)	0.54

Abbreviations: SD, standard deviation; CL, contact lens; CCT, central corneal thickness.