Herpesviridae prevalence in aqueous humor using PCR

Figures & data

Table 1 Demographic data

Characteristics	n	%
Age (years), mean ± SD (minimum–maximum)	67.7±12.5 (18–88)
Sex
Male	55	60
Female	37	40
Chronic disease
No	7	8
Yes	85	92
Diabetes mellitus	23	25
Hypertension	66	72
Dyslipidemia	50	54
Heart disease	11	12
Chronic kidney disease	15	16
Stroke	5	5
Eye disease
No	58	63
Yes	34	37
Diabetic retinopathy	7	8
Glaucoma	8	9
Retinal disease	15	16
Corneal disease	6	7
Topical eye medication
No	82	89
Antiglaucoma	7	8
Antiglaucoma and steroid	1	1
Steroid	1	1
Antibiotic	1	1
Laterality
Right eye	43	48
Left eye	47	52

Table 2 Prevalence of herpes virus serological results (N=84) and aqueous PCR results (N=66)

Virus	Positive		Negative		Borderline
	n	%	n	%	n	%
Serum for herpes virus IgG antibodies
HSV2 IgG	70	83.3	14	16.7	0	0
VZV IgG	79	94.0	2	2.4	3	3.6
EBV IgG	83	98.8	0	0	1	1.2
CMV IgG	82	97.6	1	1.2	1	1.2
Aqueous humor for herpes virus D NA by PCR
HSV1	0	0	66	100.0
HSV2	0	0	66	100.0
VZV	0	0	66	100.0
EBV	0	0	66	100.0
CMV	0	0	66	100.0

Abbreviations: CMV, cytomegalovirus; EBV, Epstein–Barr virus; HSV, herpes simplex virus; VZV, varicella zoster virus.

Table 3 Prevalence of herpes virus serological results and aqueous PCR results (N=58)

Virus	Positive		Negative		Borderline
	n	%	n	%	n	%
Serum for herpes virus IgG antibodies
HSV2 IgG	49	84.5	9	15.5	0	0
VZV IgG	54	93.1	2	3.5	2	3.5
EBV IgG	57	98.3	0	0	1	1.7
CMV IgG	56	96.6	1	1.7	1	1.7
Aqueous humor for herpes virus D NA by PCR
HSV1	0	0	58	100.0
HSV2	0	0	58	100.0
VZV	0	0	58	100.0
EBV	0	0	58	100.0
CMV	0	0	58	100.0

Abbreviations: CMV, cytomegalovirus; EBV, Epstein–Barr virus; HSV, herpes simplex virus; VZV, varicella zoster virus.