Comparison of variation of intraocular pressure in noncontact tonometry in patients subjected to phacoemulsification and trabeculectomy with phacoemulsification

Figures & data

Table 1 Distribution and comparison of the patients regarding gender and the operated eye in relation to the groups

Variable	Cases, n (%)		P-value
	Combined	Cataract
Gender			0.039a
Female	14/41.2%	88/60.7%
Male	20/58.8%	57/39.3%
Total	34/100.0%	145/100.0%
Operated eye			0.977
Right eye	23/46.9%	85/46.7%
Left eye	26/53.1%	97/53.3%
Total	49/100.0%	182/100.0%

Note: Test used: χ²,

a significant (P<0.05).

Table 2 Distribution and comparison of patients regarding the variables in relation to the groups

Variable	Combined	Cataract	P-value
Agea	71.9±8.1	72.0±9.5	<0.001b
IOP before	18.9±7.6	15.1±3.4	0.011b
IOP after 24 hours	8.3±4.4	15.7±2.6	<0.001b
IOP after 7 days	13.7±7.9	15.0±5.4	0.104
IOP after 15 days	13.4±5.3	14.0±3.3	0.200
IOP after 30 days	14.5±6.8	13.0±2.9	0.592
IOP after 3 months	12.4±3.1	11.9±2.6	0.338
IOP after 6 months	12.5±2.9	12.3±3.2	0.882
IOP after 12 months	14.4±4.1	12.6±2.5	0.042b
Axis before	96.0±41.1	84.4±41.2	0.154
Final axis	90.9±36.9	80.2±43.9	0.211
Pachymetry	522.3±39.2	530.5±38.6	0.295
ACD	2.8±0.3	3.1±0.3	<0.001b
Axial length	22.9±0.8	23.3±1.0	0.014b

Notes: Test used: Mann–Whitney,

a ANOVA,

b significant (P<0.05). Data is presented as mean ± SD.

Abbreviations: ACD, anterior chamber depth; IOP, intraocular pressure.

Figure 1 Mean of IOP difference for pre- and postoperative moments in each group.

Abbreviation: IOP, intraocular pressure.

Table 3 Distribution and comparison of patients regarding the pre- and postoperative difference in IOP in relation to the groups

Variable	Combined	Cataract	P-value
Difference (IOP before)
IOP after 24 hours	8.6±5.9	3.4±2.3	<0.001a
IOP after 7 days	7.8±7.5	3.6±3.6	0.015a
IOP after 15 days	6.3±6.1	3.1±3.2	0.025a
IOP after 30 days	6.6±6.3	3.4±2.3	0.181
IOP after 3 months	6.2±6.2	3.4±2.5	0.144
IOP after 6 months	3.2±1.4	2.4±2.3	0.056
IOP after 12 months	4.2±2.6	1.8±1.8	0.004a

Notes: Test used: Mann–Whitney,

a significant (P<0.05). Data is presented as mean ± SD.

Abbreviation: IOP, intraocular pressure.

Table 4 Linear regression test between axial length and IOP difference (post – pre) in patients subjected to phacoemulsification

Variable	R^2	B	P-value
Difference (IOP before)
IOP after 24 hours	0.081	−0.468	0.239
IOP after 7 days	0.483	−2.405	0.038a
IOP after 15 days	0.108	−1.047	0.058a
IOP after 30 days	0.054	−0.518	0.262
IOP after 3 months	0.002	−0.097	0.808
IOP after 6 months	0.149	1.108	0.113
IOP after 12 months	0.095	0.609	0.265

Note: R²= coefficient of determination, B = slope of the line, P = statistical significance,

a significant P<0.05.

Abbreviation: IOP, intraocular pressure.

Table 5 Linear regression test between ACD and IOP difference (post – pre) in eyes that were subjected to phacoemulsification

Variable	R^2	B	P-value
Difference (IOP before)
IOP after 24 hours	0.565	−4.184	0.001a
IOP after 7 days	0.163	−1.654	0.370
IOP after 15 days	0.098	−2.501	0.072
IOP after 30 days	0.000	0.057	0.963
IOP after 3 months	0.006	0.618	0.718
IOP after 6 months	0.061	1.592	0.324
IOP after 12 months	0.126	2.813	0.213

Note: R²= coefficient of determination, B = slope of the line, P = statistical significance,

a significant P<0.05.

Abbreviations: ACD, anterior chamber depth; IOP, intraocular pressure.

Table 6 Linear regression test between axial length and IOP difference (post – pre) for patients who underwent trabeculectomy with phacoemulsification

Variable	R^2	B	P-value
Difference (IOP before)
IOP after 24 hours	0.008	−0.967	0.666
IOP after 7 days	0.027	−2.104	0.445
IOP after 15 days	0.002	0.336	0.807
IOP after 30 days	0.000	0.056	0.971
IOP after 3 months	0.030	1.188	0.491
IOP after 6 months	0.003	−0.072	0.898
IOP after 12 months	0.465	−1.584	0.062

Note: R²= coefficient of determination, B = slope of the line, P = statistical significance.

Abbreviation: IOP, intraocular pressure.

Table 7 Linear regression test between ACD and difference in IOP (post – pre) for patients who underwent trabeculectomy with phacoemulsification

Variable	R^2	B	P-value
Difference (IOP before)
IOP after 24 hours	0.006	−1.979	0.703
IOP after 7 days	0.017	−4.146	0.538
IOP after 15 days	0.050	−3.669	0.237
IOP after 30 days	0.084	3.884	0.181
IOP after 3 months	0.092	4.599	0.238
IOP after 6 months	0.061	−0.999	0.594
IOP after 12 months	0.147	1.486	0.396

Note: R²= coefficient of determination, B = slope of the line, P = statistical significance.

Abbreviations: ACD, anterior chamber depth; IOP, intraocular pressure.

Table 8 Comparison between the means of the variables under study according to preoperative pressure categories for patients who underwent trabeculectomy with phacoemulsification

Variables	Mean of preoperative pressure				P-value
	≥22 mmHg	19–21 mmHg	16–18 mmHg	6–15 mmHg
Number of eyes	15	5	8	21	–
Age	69.1±8.4	72.9±9.8	74.9±6.7	75.7±6.9	0.178
IOP 1 month	11.9±6.8	17.0±10.2	20.4±4.8	13.2±4.7	0.051
IOP 3 months	12.0±3.3	11.6±4.7	12.3±1.5	11.8±2.9	0.675
IOP 6 months	13.2±3.9	13.3±1.5	15.2±0.5	11.7±2.5	0.520
IOP 12 months	16.0±6.6	15.0±5.3	15.0±1.3	12.9±3.3	0.251
Final IOP variation with SD	17.8±4.0	9.0±4.6	2.25±0.5	2.7±2.1	0.002

Notes: Test used: Kruskal–Wallis. Data is presented as mean ± SD.

Abbreviation: IOP, intraocular pressure.

Table 9 Eye distribution regarding the number of classes of anti-glaucomatous medications in the pre- and postoperative period for patients who underwent trabeculectomy with phacoemulsification

Number of drug classifications	Preoperative		Postoperative
	n	%	n	%
No medication	0.0	0.0	9	18.4
One class	0.0	0.0	15	30.6
Two classes	6	12.2	12	24.5
Three classes	37	75.6	12	24.5
Four classes	6	12.2	1	2.0