Viscodilation of Schlemm’s canal for the reduction of IOP via an ab-interno approach

Figures & data

Table 1 Population demographics (n=75 eyes)

Age (years)	Mean ± SD (range)	73.7±9.9 (37–91)
Sex, % (n)	Male	42.6 (32)
	Female	57.3 (43)
Race, % (n)	Black	5.3 (4)
	White	21.3 (16)
	Hispanic	73.3 (55)
Type of glaucoma, % (n)	POAG	100 (75)
	• Mild	37.3 (28)
	• Moderate	16.0 (12)
	• Severe	38.7 (29)
	• Unavailable	8.0 (6)

Abbreviation: POAG, primary open-angle glaucoma.

Table 2 Distribution of the percentage reduction in IOP for the whole cohort

	Frequency	Percentage	Cumulative percentage
No reduction	0	0.00	0.00
<10% of reduction	2	2.74	2.74
≥10 and <15% of reduction	4	5.48	8.22
≥15 and <20% of reduction	5	6.85	15.07
≥20 and <25% of reduction	11	15.07	30.14
≥25 and <30% of reduction	13	17.81	47.95
≥30 and <35% of reduction	6	8.22	56.16
≥35 and <40% of reduction	13	17.81	73.97
≥40%	19	26.03	100.00

Figure 1 Mean IOP in mmHg before surgery (blue bars) and 12 months after surgery (orange bars) for all eyes, for eyes treated with ABiC combined with phacoemulsification, and for eyes treated with stand-alone ABiC.

Note: *Statistically significant difference.
Abbreviations: ABiC, ab-interno canaloplasty; m, months; Phaco, phacoemulsification.

Figure 2 Mean number of medications before surgery (blue bars) and 12 months after surgery (orange bars) for all eyes, for eyes treated with ABiC combined with phacoemulsification, and for eyes treated with stand-alone ABiC.

Note: *Statistically significant difference.
Abbreviations: ABiC, ab-interno canaloplasty; m, months; Nb, number; Phaco, phacoemulsification.

Table 3 Distribution of the percentage reduction in IOP for the combined group

	Frequency	Percentage	Cumulative percentage
No reduction	0	0.00	0.00
<10% of reduction	1	2.94	2.94
≥10 and <15% of reduction	2	5.88	8.82
≥15 and <20% of reduction	1	2.94	11.76
≥20 and <25% of reduction	6	17.65	29.41
≥25 and <30% of reduction	8	23.53	52.94
≥30 and <35% of reduction	2	5.88	58.82
≥35 and <40% of reduction	7	20.59	79.41
≥40%	7	20.59	100.00

Table 4 Distribution of the percentage reduction in IOP for the stand-alone group

	Frequency	Percentage	Cumulative percentage
No reduction	0	0.00	0.00
<10% of reduction	1	2.56	2.56
≥10 and <15% of reduction	2	5.13	7.69
≥15 and <20% of reduction	4	10.26	17.95
≥20 and <25% of reduction	5	12.82	30.77
≥25 and <30% of reduction	5	12.82	43.59
≥30 and <35% of reduction	4	10.26	53.85
≥35 and <40% of reduction	6	15.38	69.23
≥40%	12	30.77	100.00

Table 5 Mean visual acuity preoperatively and 12 months postoperatively

	Visual acuity (logMAR)		P-value
	Preoperative	Postoperative
All eyes	0.50±0.47	0.35±0.49	0.002
Combined subgroup	0.58±0.41	0.29±0.41	0.001
Stand-alone subgroup	0.44±0.52	0.41±0.56	0.849

Abbreviation: logMAR, logarithm of the minimum angle of resolution.