Macular microstructure and visual acuity after macula-off retinal detachment repair by 23-gauge vitrectomy plus silicone endotamponade

Figures & data

Table 1 Age, gender, and duration of RD in groups I and II

	Group I (n=20)	Group II (n=16)	P-value
Age (years)			0.498
Mean ± SD	51±12	46±19
Gender			0.343
Male	12 (60%)	12 (75%)
Female	8 (40%)	4 (25%)
Duration (days)			<0.001*
Mean ± SD	16±2.3	22.5±3.6

Note:

* Statistically significant.

Abbreviation: RD, retinal detachment.

Table 2 OCT findings in both groups

	N	%
Disruption of retinalmicrostructure
Normal	14	38.9
Mild	10	27.8
Severe	12	33.3
ERM
No	31	86.1
Early (≤3 months)	3	8.3
Late (≥6 months)	2	5.5

Abbreviations: ERM, epiretinal membrane; OCT, optical coherence tomography.

Table 3 Specific OCT findings in each group

	Group I (n=20)		Group II (n=16)		P-value
	N	%	N	%
Disruption of retinalmicrostructure					<0.001
Normal	14	70.0	0	0.0
Mild	6	30.0	4	25.0
Severe	0	0.0	12	75.0
ERMa					0.005
No	18	90.0	13	81.3
Early (≤3 months)	0	0.0	3	18.7
Late (≥6 months)	2	10.0	0	0.0

Note:

a Only two patients in group I and three in group II had epiretinal membrane.

Abbreviations: ERM, epiretinal membrane; OCT, optical coherence tomography.

Figure 1 No disruption in the EZ or the ELM.

Abbreviations: ELM, external limiting membrane; EZ, ellipsoid zone.

Figure 2 Disruption of EZ with normal ELM.

Abbreviations: ELM, external limiting membrane; EZ, ellipsoid zone; IS/OS, inner segment/outer segment.

Figure 3 Combined disruption of the EZ and ELM.

Abbreviations: EZM, external limiting membrane; EZ, ellipsoid zone; IS/OS, inner segment/outer segment.

Figure 4 Early ERM ≤3 months with CME.

Abbreviations: ERM, epiretinal membrane; CME, cystoid macular edema.

Figure 5 Late ERM >6 months with CME.

Abbreviations: CME, cystoid macular edema; ERM, epiretinal membrane.

Table 4 OCT parameters of cases with no ERM and with mild-to-moderate disruption

	Mean±SD		P-value
	Group I	Group II
Average thickness (μm)			<0.001
Operated eye	251	9
Fellow eye	263	10
Center thickness (μm)			<0.001
Operated eye	190	26
Fellow eye	210	20
Total volume (mm^2)			<0.001
Operated eye	7.1	0.2
Fellow eye	7.5	0.3
ONLT (μm)			<0.001
Operated eye	110	23
Fellow eye	129	19

Abbreviations: ERM, epiretinal membrane; OCT, optical coherence tomography; ONLT, outer nuclear layer thickness.

Table 5 OCT parameters of cases with no ERM and with severe disruption

	Mean±SD		P-value
	Group I	Group II
Average thickness (μm)			0.005
Operated eye	225	11
Fellow eye	267	15
Center thickness (μm)			0.005
Operated eye	138	34
Fellow eye	184	22
Total volume (mm^2)			0.005
Operated eye	6.6	0.5
Fellow eye	7.5	0.4
ONLT (μm)			0.005
Operated eye	71	21
Fellow eye	116	19

Abbreviations: ERM, epiretinal membrane; OCT, optical coherence tomography; ONLT, outer nuclear layer thickness.

Table 6 Comparison of macular thickness and ONLT between operated eyes with no ERM from groups I and II

	Group I (n=18)		Group II (n=13)		P-value
	Mean	±SD	Mean	±SD
Average thickness (μm)	251	9	225	11	<0.001
Center thickness (μm)	190	26	138	34	<0.001
Total volume (mm^3)	7.1	0.2	6.6	0.5	0.003
ONLT (μm)	110	23	71	21	0.001

Abbreviations: ERM, epiretinal membrane; ONLT, outer nuclear layer thickness.

Figure 6 Correlation between 6-month postoperative LogMAR BCVA and severity of disruption.

Abbreviations: BCVA, best-corrected visual acuity; VA, visual acuity.

Figure 7 Correlation between 6-month postoperative LogMAR BCVA and ONLT.

Abbreviations: BCVA, best-corrected visual acuity; ONLT, outer nuclear layer thickness; VA, visual acuity.

Figure 8 Correlation between 6-month postoperative LogMAR BCVA and average macular thickness.

Abbreviation: BCVA, best-corrected visual acuity.

Figure 9 Correlation between 6-month postoperative LogMAR BCVA and central macular thickness.

Abbreviation: BCVA, best-corrected visual acuity.

Figure 10 Correlation between 6-month postoperative LogMAR BCVA and total macular volume.

Abbreviation: BCVA, best-corrected visual acuity.