Correlation between body mass index and ocular parameters

Figures & data

Table 1 Demographic data

Characteristics	Total (N=120)	Normal weight (N=53)	Overweight (N=67)	P-value
Age (years)	47.00±14.00	45.60±11.51	47.00±15.00	0.649^b
Sex (male%)	43.33%	35.85%	49.25%	0.14^c
SBP (mmHg)	125.28±17.19	119.58±15.71	129.78±17.09	0.001^a*
DBP (mmHg)	80.78±11.79	76.45±8.56	84.20±12.88	0.000^a*
Alcohol (yes%)	35.83%	45.28%	28.36%	0.055 ^c
Current smoker (yes%)	10.83%	7.53%	13.43%	0.303^c
Body compositions
BMI (kg/m^2)	23.42±6.24	20.89±1.15	26.67±5.26	0.000^b*
W/H ratio	0.88±0.09	0.85±0.09	0.89±0.06	0.000^b*

Notes: ^*Statistically significant; ^aindependent Student’s t-test; ^bMann–Whitney U test; ^c Chi-square test.

Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure; BF, body fat; W/H ratio, waist–hip ratio.

Table 2 Comparison of anterior segment parameters of eyes between groups

Parameters	Total (N=120)	Normal weight (N=53)	Overweight (N=67)	P-value
HACC (mm)	7.76±0.29	7.76±0.29	7.77±0.29	0.854^a
VACC (mm)	7.67±0.28	7.67±0.28	7.67±0.28	0.859^a
IOP (mmHg)	12.30±3.20	11.86±2.12	12.80±3.40	0.002^b*
CCT (µm)	527.45±34.54	523.64±33.70	530.46±35.15	0.282^a
ACD (mm)	2.79±0.34	2.76±0.33	2.81±0.35	0.387^a
ACA (degree)	29.80±8.47	30.67±9.45	29.10±7.61	0.326^a

Notes: *Statistically significant; ^aindependent Student’s t-test; ^bMann–Whitney U test.

Abbreviations: HACC, horizontal anterior corneal curvature; VACC, vertical anterior corneal curvature; IOP, intraocular pressure; CCT, central corneal thickness; ACD, anterior chamber depth; ACA, anterior chamber angle.

Table 3 Comparison of posterior segment parameters of eyes between groups

Parameters	Total (N=120)	Normal weight (N=53)	Overweight (N=67)	P-value
MT (µm)	241.00±25.50	237.00±19.50	247.36±20.61	0.009^b*
GCT (µm)	85.00±7.75	84.00±8.50	86.00±9.00	0.036^b*
RNFLT (µm)	100.00±11.75	99.00±13.00	99.63±10.18	0.589^b
CDR	0.53±0.15	0.53±0.16	0.53±0.14	0.855^a
CT (µm)	441.74±60.24	445.36±64.17	438.88±57.28	0.566^a

Notes: *Statistically significant; ^aindependent Student’s t-test; ^bMann–Whitney U test.

Abbreviations: MT, macular thickness; GCT, ganglion cell thickness; RNFLT, retinal nerve fiber layer thickness; CDR, cup disc ratio; CT, choroid thickness.

Table 4 Correlation between BMI and parameters of eyes

Parameters	Univariate analysis			Multivariate analysis
	β	95% CI	P-value	β	95% CI	P-value
Anterior segment parameters
HACC (mm)	0.079	−1.859 – 4.710	0.392	–	–	–
VACC (mm)	−0.014	−3.667 to 3.155	0.882	–	–	–
IOP (mmHg)	0.269	0.193 to 0.916	0.003*	–	–	–
CCT (µm)	0.048	−0.020 to 0.035	0.606	–	–	–
ACD (mm)	0.198	0.302 to 5.788	0.030*	0.410	0.008 to 0.045	0.005*
ACA (degree)	−0.030	−0.131 to 0.094	0.747	–	–	–
Posterior segment parameters
GCT (µm)	0.089	−0.055 to 0.162	0.332	–	–	–
MT (µm)	0.102	−0.020 to 0.072	0.266	–	–	–
RNFLT (µm)	0.023	−0.058 to 0.074	0.807	–	–	–
CT (µm)	−0.004	−0.016 to 0.015	0.964	–	–	–
CDR	0.070	−3.830 to 8.610	0.448	–	–	–

Note: *Statistically significant.

Abbreviations: HACC, horizontal anterior corneal curvature; VACC, vertical anterior corneal curvature; IOP, intraocular pressure; CCT, central corneal thickness; ACD, anterior chamber depth; ACA, Anterior chamber angle; GCT, ganglion cell thickness; MT, macular thickness; RNFLT, retinal nerve fiber layer thickness; CT, choroidal thickness; CDR, cup disc ratio.

Figure 1 Correlation between BMI and intraocular pressure.

Figure 2 Correlation between BMI and anterior chamber depth.