Figures & data
Table 1 Baseline characteristics of the study participants in the FAc and DEX implant treatment groups
Figure 1 Study design and patient disposition. In the fluocinolone acetonide (FAc) implant cohort, 11 (from 10 patients) of the 29 eyes had been treated with a prior dexamethasone (DEX) implant. A subgroup of these (n=5 eyes from 5 patients) were assessed based on the FAc implant group having at least 12 months follow-up post-treatment and only one DEX implant being given prior to the FAc implant.
![Figure 1 Study design and patient disposition. In the fluocinolone acetonide (FAc) implant cohort, 11 (from 10 patients) of the 29 eyes had been treated with a prior dexamethasone (DEX) implant. A subgroup of these (n=5 eyes from 5 patients) were assessed based on the FAc implant group having at least 12 months follow-up post-treatment and only one DEX implant being given prior to the FAc implant.](/cms/asset/73cffc9f-c34d-4eba-a17b-8d29be19a5a3/doph_a_12176391_f0001_b.jpg)
Figure 2 Changes in BCVA (A) and CFT (B) in 14 eyes over 6 months post DEX implantation. n: number of unique study eyes at individual time points. The baseline BCVA was 40.6 letters; and the baseline CFT was 470.5 µm.
![Figure 2 Changes in BCVA (A) and CFT (B) in 14 eyes over 6 months post DEX implantation. n: number of unique study eyes at individual time points. The baseline BCVA was 40.6 letters; and the baseline CFT was 470.5 µm.](/cms/asset/2b5b074e-a105-4092-8046-b3e560ae098d/doph_a_12176391_f0002_c.jpg)
Figure 3 Effect on BCVA (A) and CFT (B) 24 months post-FAc implantation in 8 eyes that completed a 24-month follow-up. Five of the eyes had previously been treated with a DEX implant. The baseline BCVA was 31.5 letters; and the baseline CFT was 594.8 µm.
![Figure 3 Effect on BCVA (A) and CFT (B) 24 months post-FAc implantation in 8 eyes that completed a 24-month follow-up. Five of the eyes had previously been treated with a DEX implant. The baseline BCVA was 31.5 letters; and the baseline CFT was 594.8 µm.](/cms/asset/6cf0b7b0-1aec-48e6-ab11-d8077d61ba35/doph_a_12176391_f0003_b.jpg)
Figure 4 Changes in BCVA (A, C) and CFT (B, D) in 5 eyes initially treated with a DEX implant (squares) and followed for 6 months (A, B) that were subsequently switched to a FAc implant (circles) and followed for an additional 12 months post FAc implant switch (C, D). n: number of unique study eyes at individual time points. The baseline BCVA values were as follows: a) 38.0 letters; c) 29.0 letters. The baseline CFT values were as follows: b) 499.4 µm; d) 541.0 µm.
![Figure 4 Changes in BCVA (A, C) and CFT (B, D) in 5 eyes initially treated with a DEX implant (squares) and followed for 6 months (A, B) that were subsequently switched to a FAc implant (circles) and followed for an additional 12 months post FAc implant switch (C, D). n: number of unique study eyes at individual time points. The baseline BCVA values were as follows: a) 38.0 letters; c) 29.0 letters. The baseline CFT values were as follows: b) 499.4 µm; d) 541.0 µm.](/cms/asset/b70e6ea9-2254-4ca7-ba01-4136cbd4a512/doph_a_12176391_f0004_b.jpg)
Table 2 Mean IOP pressures and treatments in the participants in the DEX (A) and FAc implant (B) treatment groups