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Original Research

Efficacy and safety of tafluprost 0.0015% – retrospective analysis of real-world data from the Philippines

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Pages 1627-1634 | Published online: 27 Aug 2019

Figures & data

Figure 1 Disease characteristics among subject population.

Abbreviations: PAC, primary angle-closure; PACG, primary angle-closure glaucoma; POAG, primary open-angle glaucoma; OHT, ocular hypertension; NTG, normal-tension glaucoma.

Figure 1 Disease characteristics among subject population.Abbreviations: PAC, primary angle-closure; PACG, primary angle-closure glaucoma; POAG, primary open-angle glaucoma; OHT, ocular hypertension; NTG, normal-tension glaucoma.

Table 1 Pre-study medication of patients switched to tafluprost (n=73)

Figure 2 Mean IOP change from baseline in mmHg and percentage (%) in all eyes treated with tafluprost 0.0015% with 0.001 BAK preservative. Primary endpoint was at 3 months. Bars represent standard deviation.

Figure 2 Mean IOP change from baseline in mmHg and percentage (%) in all eyes treated with tafluprost 0.0015% with 0.001 BAK preservative. Primary endpoint was at 3 months. Bars represent standard deviation.

Figure 3 Sub-group analysis based on therapeutic pattern. The treatment naïve subgroup had no previous glaucoma treatment. The add-on subgroup had tafluprost added to existing glaucoma medication to try to achieve further IOP reduction. The replacement subgroup had their glaucoma medication replaced with tafluprost. Primary endpoint was at 3 months. Bars represent standard deviation.

Figure 3 Sub-group analysis based on therapeutic pattern. The treatment naïve subgroup had no previous glaucoma treatment. The add-on subgroup had tafluprost added to existing glaucoma medication to try to achieve further IOP reduction. The replacement subgroup had their glaucoma medication replaced with tafluprost. Primary endpoint was at 3 months. Bars represent standard deviation.

Figure 4 Sub-group analysis comparing degree of mean IOP reduction in eyes with primary open-angle glaucoma and ocular hypertension (POAG/OHT) sub-group compared to those with primary angle closure and primary angle-closure glaucoma post-laser iridotomy with at least 90 degrees open-angle (PAC/PACG) sub-group. Primary endpoint was at 3 months. Bars represent standard deviation.

Figure 4 Sub-group analysis comparing degree of mean IOP reduction in eyes with primary open-angle glaucoma and ocular hypertension (POAG/OHT) sub-group compared to those with primary angle closure and primary angle-closure glaucoma post-laser iridotomy with at least 90 degrees open-angle (PAC/PACG) sub-group. Primary endpoint was at 3 months. Bars represent standard deviation.

Table 2 Adverse reactions recorded