Effect Of Intracameral Phenylephrine And Ketorolac 1.0%/0.3% On Intraoperative Pain And Opioid Use During Cataract Surgery

Figures & data

Table 1 Preoperative And Operative Characteristics Of Study Subjects

Characteristics	Study Group	Control Group	P Value
	Mean±SD	Mean±SD
Age (years)	72.1±8.8	73.5±7.2	0.562
Duration of surgery (minutes)	7.9±1.6	9.1±2.0	0.011
Intraocular pressure (mmHg)	16.3±1.9	15.6±2.2	0.208
Cataract severity grade (0-4)	1.8±0.7	2.1±0.7	0.169
	Number of patients n (%)
Gender			0.759
Males	19 (46.3)	8 (42.1)
Females	22 (53.7)	11 (57.9)
Type of surgery			0.896
FLACS	23 (56.1)	11 (57.9)
Conventional phacoemulsification	18 (43.9)	8 (42.1)
Surgical eye			0.630
Dominant eye	21 (51.2)	11 (57.9)
Non-dominant eye	20 (48.8)	8 (42.1)

Note: Statistical significance: P < 0.05.

Abbreviations: FLACS, femtosecond laser-assisted cataract surgery; mmHg, millimeter of mercury.

Figure 1 Mean VAS pain scores by control and study groups. The control group received intracameral epinephrine in the irrigating solution during cataract surgery. The study group received intracameral phenylephrine and ketorolac 1%/0.3%.

Abbreviation: VAS, visual analog scale.

Figure 2 (A–D) Comparison of pain and fentanyl use between the control (epinephrine) and study (phenylephrine and ketorolac 1%/0.3%) groups. (A) Proportion of patients by VAS pain scores (0–10); (B) Proportion of patients with no pain to mild pain (VAS scores 0–3); (C) Proportion of patients requiring intravenous fentanyl for cataract surgery; (D) Proportion of patients not receiving intravenous fentanyl for cataract surgery with VAS scores 0–3 (no pain to mild pain).

Abbreviations: VAS, visual analog scale; IV, intravenous.