Baseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy

Figures & data

Figure 1 OCT showing hyper-reflective deposits in the intra-retinal layer (circle), PED (Triangle), and neurosensory retinal detachment.

Figure 2 The disrupted IS/OS junction is demonstrated by a thin arrow.

Figure 3 Locally thickened neurosensory retina (“retinal dipping”, star), connected by a hyper-reflective flow, suggesting high fibrin/protein content (arrow).

Table 1 Comparision of OCT Features in Resolved and Non-Resolved CSCR

OCT Parameters	Resolved CSCR (n=22) (%)	Non-Resolved CSCR (n=26) (%)	P-Value
Pigment Epithelial Detachment	4 (18.18)	7 (26.92)	0.473^†
RPE bumps	11 (50)	19 (73.07)	0.10^†
Discontinuation in IS/OS junction	5 (22.72)	20 (76.92)	0.00^†*
Fibrinous exudates in sub-retinal space	0 (0.0)	4 (15.38)	0.114^¥
Hyper-reflective deposits in intra or sub-retinal layer	2 (9.09)	22 (84.61)	0.00^†*

Notes: *P-value<0.05. ^†Chi-square test. ^¥Fischer’s exact test.

Abbreviations: RPE, retinal pigment epithelium; OCT, Optical Coherence Tomography; CSCR, Central Serous Chorioretinopathy; IS, Inner Segment; OS, Outer Segment.

Table 2 OCT Findings in Relation with Visual Outcome

	Visual Outcome		P-Value
	Good (n=42) (%)	Poor (n=6) (%)
Pigment epithelial detachment	9 (21.42)	2 (33.33)	0.609
RPE bumps	27 (64.28)	3 (50)	0.658
Discontinuation in IS/OS junction	19 (45.23)	6 (24.0)	0.01*
Fibrinous exudates in sub-retinal space	3 (7.14)	1 (16.66)	0.425
Hyper-reflective deposits in intra or sub-retinal layer	18 (42.85)	6 (100)	0.02*

Notes: *P-value<0.05, Fischer’s exact test.

Abbreviations: RPE, retinal pigment epithelium; OCT, Optical Coherence Tomography; IS, Inner Segment; OS, Outer Segment.