Assessment of the Effect of Vitiligo on Subfoveal Choroidal Thickness Using Spectral-Domain Optical Coherence Tomography

Figures & data

Table 1 Refraction, Corrected Distance Visual Acuity, and Intraocular Pressures of Cases and Controls

Variables		Cases	Controls	p-value
		N = 31	N = 32
Spherical Equivalent (Diopter)	Mean ± SD	−0.73 ± 1.54	−1.36 ± 1.57	0.1131
	Range	−3.5–2	−3.75–2
CDVA (decimal format)	Mean ± SD	0.85 ± 0.19	0.95 ± 0.1	0.0109*
	Range	0.3–1	0.8–1
IOP (mmHg)	Mean ± SD	15.68 ± 2.44	15.63 ± 2.39	0.9348
	Range	11–22	11–20

Note: *Statistically significant.

Table 2 Major Slit-Lamp and Fundus Examination Findings in Cases and Controls

Variables		Cases	Controls	p-value
		N = 31	N = 32
Slit Lamp N (%)	Focal Iris Atrophy	8 (25.8)	0 (0)	0.0023*
	Cataract	5 (16.1)	4 (12.5)	0.6854
Fundus N (%)	RPE Mottling	12 (38.7)	2 (6.25)	0.0021*
	Hypopigmented Lesion	3 (9.68)	0 (0)	0.0736
	Peripapillary Atrophy	3 (9.68)	2 (6.25)	0.6174

Note: *Statistically significant.

Figure 1 A 32-year-old female with two years duration of illness, (A) fundus photography revealing a hypopigmented lesion detected in the lower nasal quadrant of the right eye, and (B) SFCT measurement using SD-OCT in the right eye.

Table 3 Correlation Between SFCT and Different Variables

Variables		r	p-value
SFCT Cases (n = 31)	Disease Duration	−0.1781	0.3381
	Treatment Duration	−0.1583	0.3959
	VASI Score	−0.201	0.2783
	Periocular Skin Involvement	−0.0907^†	0.6274
SFCT Total (n = 63)	Age	−0.5013	< 0.0001*
	Sex	0.2139^†	0.0922
	Spherical Equivalent	−0.0861	0.5027
	CDVA	0.2464	0.0516

Notes: ^†Point-Biserial correlation. *Statistically significant.