Three-Year Outcomes of Simultaneous Accelerated Corneal Crosslinking and Femto-LASIK for the Treatment of High Myopia in Asian Eyes

Figures & data

Table 1 Postoperative Uncorrected Distance Visual Acuity (UDVA) and Efficacy Index

	1 Year Post-op 1 Year (n=67)	2 Years Post-op (n=65)	3 Years Post-op (n=43)	p-value*
% of eyes with UDVA of 6/12 or better, % (95% CI)	98.5 (91.3, 99.9)	95.4 (86.7, 98.9)	97.7 (86.8, 99.9)	0.643
% of eyes had UDVA of 6/6 or better, % (95% CI)	71.6 (59.9, 81.1)	73.8 (61.9, 83.1)	65.1 (50.1, 77.6)	0.629
Efficacy Index mean± SD	0.95 ± 0.18	0.97 ± 0.24	0.92 ± 0.19	0.391

Notes: *p values calculated using Fisher’s Exact test for UDVA and one way ANOVA for efficacy index.

Abbreviations: post-op, postoperatively; UDVA, uncorrected distance visual acuity; CI, confidence interval; SD, standard deviation.

Figure 1 Bar chart showing the percentage of eyes with uncorrected distance visual acuities (UDVA) pre-operatively and up to 3 years post-operatively.

Table 2 Percentage of Eyes with Spherical Equivalent (SE) Within ± 1D and ± 0.5D of Attempted Correction

	1 Year Post-op (n=62)	2 Years Post-op (n=65)	3 Years Post-op (n=42)	p-value*
% of eyes with SE within ± 1D of attempted correction, % (95% CI)	95.2 (86.2, 98.9)	95.4 (86.7, 98.9)	97.7 (86.8, 99.9)	0.542
% of eyes with SE within ± 0.5D of attempted correction, % (95% CI)	85.5 (74.4, 92.4)	90.8 (80.9, 96.0)	83.3 (69.1, 92.0)	0.478

Note: *p values calculated using Fisher’s Exact test.

Abbreviations: post-op, postoperatively; SE, spherical equivalent; D, diopters; CI, confidence interval.

Figure 2 Graph showing the correlation between the attempted and achieved spherical equivalent (SE) corrections.

Table 3 Preoperative and Postoperative Mean Spherical Equivalent (SE)

	Pre-op (n=163)	Attempted Correction (n=163)	1 Year Post-op (n=62)	2 Years Post-op (n=65)	3 Years Post-op (n=42)	p-value*
Mean SE ± SD, D	−8.60 ± 1.47	−8.84 ± 1.41	0.14 ± 0.46	0.07 ± 0.40	−0.10 ± 0.45	0.029
Range, D	−11.75 to −4.75	−11.88 to −5.25	−1.63 to 1.50	−1.50 to 0.88	−1.50 to 0.75	−

Notes: *p values calculated using one way ANOVA test comparing between 1, 2 and 3-year post-operatively (pairwise analysis showed a statistical significance between post-operative year 1 and year 3 [p = 0.026, adjusted Bonferroni correction]).

Abbreviations: pre-op, preoperatively; post-op, postoperatively; SE, spherical equivalent; SD, standard deviation; D, diopters; CI, confidence interval.

Figure 3 Graph showing the stability of mean spherical equivalent (SE) refraction post LASIK Xtra over 3 years of follow-up.

Figure 4 Bar chart showing the percentage of eyes that had changes in Snellen lines of best corrected visual acuity (BCVA) over 3 years of follow-up.