Signs and Symptoms of Ocular Surface Disease: The Reasons for Patient Dissatisfaction with Glaucoma Treatments

Figures & data

Table 1 Patient Demographic and Clinical Data

		Total (N=793)
Age (years)	N	778
18–39	n (%)	25 (3.2%)
40–49	n (%)	55 (7.1%)
50–59	n (%)	128 (16.5%)
60–69	n (%)	240 (30.8%)
70–79	n (%)	214 (27.5%)
+80	n (%)	116 (14.9%)
	Missing	15
Gender	N	720
Male	n (%)	367 (51.0%)
Female	n (%)	353 (49.0%)
	Missing	73
Time from glaucoma or ocular hypertension diagnosis (years)	N	657
	Mean (SD)	8.12 (7.44)
	Median (Q1;Q3)	6.00 (3.00;12.00)
	Min;Max	0.0;56.0
	Missing	136
Type of glaucoma - Primary	N	667
Open angle	n (%)	634 (95.1%)
Angle closure	n (%)	32 (4.8%)
Congenital	n (%)	1 (0.1%)
	Missing	126
Type of glaucoma - Secondary	N	88
Pigmentary	n (%)	22 (25.0%)
Exfoliative	n (%)	21 (23.9%)
Others	n (%)	45 (51.1%)
	Missing	705
IOP Assessment - Right Eye (mm Hg)	N	744
	Mean (SD)	16.34 (4.58)
	Median (Q1;Q3)	16.00 (14.00;18.00)
	Min;Max	4.0;46.0
	Missing	49
IOP Assessment - Left Eye (mm Hg)	N	742
	Mean (SD)	16.27 (4.45)
	Median (Q1;Q3)	16.00 (13.00;18.00)
	Min;Max	6.0;46.0
	Missing	51
Ocular Hypertension - Right Eye	n (%)	251 (31.7%)
Stage of glaucoma - Right Eye	N	515
Early glaucoma (< 6dB)	n (%)	268 (52.0%)
Moderate glaucoma (6–12 dB)	n (%)	139 (27.0%)
Severe glaucoma (> 12 dB)	n (%)	108 (21.0%)
	Missing	278
Ocular Hypertension - Left Eye	n (%)	243 (30.6%)
Stage of glaucoma - Left Eye	N	518
Early glaucoma (< 6dB)	n (%)	260 (50.2%)
Moderate glaucoma (6–12 dB)	n (%)	162 (31.3%)
Severe glaucoma (> 12 dB)	n (%)	96 (18.5%)
	Missing	275
Ocular Hypertension - Both Eye	n (%)	289 (36.5%)
	Missing	1
Stage of glaucoma - Both Eye	N	567
Early glaucoma (< 6dB)	n (%)	239 (42.2%)
Moderate glaucoma (6–12 dB)	n (%)	177 (31.2%)
Severe glaucoma (> 12 dB)	n (%)	151 (26.6%)
	Missing	226

Table 2 Treatment Change and Reason for Change

Duration of Previous Treatment (Years)	N	702
	Mean (SD)	7.83 (7.08)
	Median (Q1;Q3)	6.00 (3.00;12.00)
	Min;Max	0.0;46.0
	Missing	91
Number for treatment change	N	785
	Mean (SD)	1.56 (1.98)
	Median (Q1;Q3)	1.00 (0.00;2.00)
	Min;Max	0.0;15.0
	Missing	8
At least one reason for treatment change reported	n (%)	530 (66.8%)
Insufficient efficacy	n (%)	419 (52.8%)
Local intolerance	n (%)	161 (20.3%)
Systemic intolerance	n (%)	34 (4.3%)
Patient’s request	n (%)	26 (3.3%)
Insufficient compliance	n (%)	18 (2.3%)
Other	n (%)	31 (3.9%)