Clinical Outcomes After Topography-Guided Refractive Surgery in Eyes with Myopia and Astigmatism – Comparing Results with New Planning Software to Those Obtained Using the Manifest Refraction

Figures & data

Table 1 Demographics, Preoperative Refractive Status and Follow-Up Time

	PAE	Manifest	p value
n	115	133
Age (years)	31.5 ± 6.0 (20 to 49)	30.2 ± 6.3 (18 to 54)	0.11
Sex (M/F)	62/53	67/66	0.58
Preoperative refraction (D)
Sphere	−3.48 ± 1.93 (−8.00 to −0.25)	−3.81 ± 2.05 (−7.75 to 0.00)	0.21
Cylinder	−0.86 ± 0.66 (−3.00 to 0.00)	−1.15 ± 0.82 (−3.25 to 0.00)	< 0.01
Spherical equivalent	−3.91 ± 1.93 (−8.625 to −1.00)	−4.38 ± 2.03 (−8.38 to −0.75)	0.07
Magnitude of treatment cylinder (D)	−0.95 ± 0.64 (−3.00 to 0.03)	−1.04 ± 0.73 (−2.75 to 0.00)	0.31
Preoperative CDVA (logMAR)	−0.01 ± 0.03 (−0.10 to 0.00)	−0.00 ± 0.02 (−0.10 to 0.04)	0.01
Follow-up time (days)	62 ± 31 (27 to 137)	84 ± 32 (27 to 158)	< 0.01
Follow-up between 30 and 120 days	103/115 (90%)	116/133 (87%)	0.57

Abbreviations: PAE, Phorcides Analytical Engine; D, diopter; CDVA, best-corrected distance visual acuity; logMAR, logarithm of the minimum angle of resolution.

Table 2 Clinical Outcomes (n = 133 Manifest, 115 PAE)

Outcome Variables	Group	Mean	Std. Dev.	Minimum	Maximum	p
UDVA (logMAR)	Manifest	−0.03	0.07	−0.14	0.34	0.003
	PAE	−0.05	0.06	−0.20	0.10
CDVA (logMAR)	Manifest	−0.05	0.05	−0.14	0.06	0.020
	PAE	−0.06	0.05	−0.20	0.06
Sphere (D)	Manifest	0.12	0.23	−0.25	1.50	0.13
	PAE	0.08	0.16	−0.25	0.50
Cylinder (D)	Manifest	0.09	0.18	0.00	0.75	0.005
	PAE	0.03	0.11	0.00	0.50
MRSE (D)	Manifest	0.08	0.23	−0.38	1.38	0.650
	PAE	0.07	0.16	−0.38	0.50

Abbreviations: PAE, Phorcides Analytical Engine; Std. Dev., standard deviation; D, diopter; MRSE, mean refraction spherical equivalent; CDVA, best-corrected distance visual acuity; UDVA, uncorrected distance visual acuity; logMAR, log of the minimum angle of resolution.

Figure 1 Postoperative uncorrected visual acuity by group.

Abbreviation: PAE, Phorcides Analytical Engine.

Figure 2 Postoperative best-corrected visual acuity by group.

Abbreviation: PAE, Phorcides Analytical Engine.

Figure 3 Residual refractive cylinder by group.

Abbreviation: PAE, Phorcides Analytical Engine.

Table 3 Difference Between Preoperative CDVA and Postoperative UDVA and CDVA

Comparison to Preoperative CDVA	Group	Total	1+ Lines Better	Within 1 Line	1+ Lines Worse
Postoperative UDVA	Manifest	133	26 (19%)	105 (79%)	2 (2%)
	PAE	115	30 (26%)	84 (73%)	1 (1%)
Postoperative CDVA	Manifest	133	34 (26%)	99 (74%)	0
	PAE	115	33 (29%)	82 (71%)	0

Abbreviations: PAE, Phorcides Analytical Engine; CDVA, best-corrected distance visual acuity; UDVA, uncorrected distance visual acuity.